Protein: KI2S2
Killer cell immunoglobulin-like receptor 2DS2 (CD158 antigen-like family member J) (NK receptor 183 ActI) (Natural killer-associated transcript 5) (NKAT-5) (p58 natural killer cell receptor clone CL-49) (p58 NK receptor CL-49) (CD antigen CD158j)

Gene: KI2S2, KIR2DS2
Organism: Homo sapiens
Interactions: 38
UniProt ID: P43631

Gene Ontology (top 5):
GO:0002222 - stimulatory killer cell immunoglobulin-like receptor signaling pathway
GO:0002764 - immune response-regulating signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0006955 - immune response

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850863

KI3L1
Killer cell immunoglobulin-like receptor 3DL1

3

14

High-throughput

0.861

High

850898

KI2LA
Killer cell immunoglobulin-like receptor 2DL5A

3

14

High-throughput

0.827

High

378670

IGJ
Immunoglobulin J chain

3

0

High-throughput

0.816

High

379730

IGHA2
Immunoglobulin heavy constant alpha 2

2

4

High-throughput

0.712

High

850892

KI2S5
Killer cell immunoglobulin-like receptor 2DS5

2

14

High-throughput

0.712

High

850893

KI2S1
Killer cell immunoglobulin-like receptor 2DS1

2

14

High-throughput

0.712

High

850797

KI2L2
Killer cell immunoglobulin-like receptor 2DL2

1

14

High-throughput

0.691

High

850891

KI2S3
Killer cell immunoglobulin-like receptor 2DS3

1

14

High-throughput

0.691

High

402876

ANXA1
Annexin A1

3

2

High-throughput

0.667

High

850903

PAUF
Pancreatic adenocarcinoma up-regulated factor

3

1

High-throughput

0.667

High

850906

MUC5B
Mucin-5B

3

5

High-throughput

0.667

High

850910

CRNN
Cornulin

3

3

High-throughput

0.667

High

520778

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

20

Small-scale

0.647

High

850890

KI2S2
Killer cell immunoglobulin-like receptor 2DS2

1

14

Small-scale

0.647

High

850900

MUC7
Mucin-7

3

0

High-throughput

0.638

High

322711

RHBT3
Rho-related BTB domain-containing protein 3

3

3

High-throughput

0.609

High

370059

CYTS
Cystatin-S

3

3

High-throughput

0.609

High

479915

CYTT
Cystatin-SA

3

3

High-throughput

0.609

High

850904

BPIA2
BPI fold-containing family A member 2

3

1

High-throughput

0.609

High

850911

RBGP1
Rab GTPase-activating protein 1

3

2

High-throughput

0.609

High

850899

INT1
Integrator complex subunit 1

2

0

High-throughput

0.585

High

230946

TYOBP
TYRO protein tyrosine kinase-binding protein

2

3

Small-scale

0.584

High

379624

IGHA1
Immunoglobulin heavy constant alpha 1

1

4

High-throughput

0.575

High

317809

LTN1
E3 ubiquitin-protein ligase listerin

2

2

High-throughput

0.558

High

370168

CYTN
Cystatin-SN

2

3

High-throughput

0.558

High

850895

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

2

3

High-throughput

0.558

High

702390

CYTD
Cystatin-D

1

3

High-throughput

0.489

High

850896

S27A3
Long-chain fatty acid transport protein 3

1

2

High-throughput

0.479

High

850908

CKLF6
CKLF-like MARVEL transmembrane domain-containing protein 6

1

2

High-throughput

0.479

High

850909

ERAP1
Endoplasmic reticulum aminopeptidase 1

1

1

High-throughput

0.479

High

850907

EXOC1
Exocyst complex component 1

1

0

High-throughput

0.458

High

850894

FAKD3
FAST kinase domain-containing protein 3, mitochondrial

1

3

High-throughput

0.437

High

850901

ELYS
Protein ELYS

1

2

High-throughput

0.437

High

850902

INT12
Integrator complex subunit 12

2

0

High-throughput

0.318

High

850897

CHD1L
Chromodomain-helicase-DNA-binding protein 1-like

1

0

High-throughput

0.249

Low

850905

PGAP4
GPI-N-acetylgalactosamine transferase PGAP4

1

0

High-throughput

0.249

Low

517208

AMY1B
Alpha-amylase 1B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025