HitPredict

Interactor 1: ACHA4 (P43681)
Neuronal acetylcholine receptor subunit alpha-4
Gene: CHRNA4

Interactor 2: RAPSN (Q13702)
43 kDa receptor-associated protein of the synapse (RAPsyn) (43 kDa postsynaptic protein) (Acetylcholine receptor-associated 43 kDa protein) (RING finger protein 205)
Gene: RAPSN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	11342559
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007268 - chemical synaptic transmission GO:0007271 - synaptic transmission, cholinergic
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 627 Hs			1 412
+	Hs
		851149 ACHA4_HUMAN (1-627): 0: 742: 100.00		TMTC3_HUMAN (216-411): 8.03e-13: 72.5: 8.45
+	Mm
		485962 ACHB_MOUSE (450-621): 7.57e-36: 143: 21.51		RAPSN_MOUSE (1-412): 3.52e-66: 218: 96.12
+	Mm
		415156 ACHA_MOUSE (499-626): 2.41e-25: 111: 24.27		RAPSN_MOUSE (1-412): 3.52e-66: 218: 96.12
+	Hs
		607942 ACHB2_HUMAN (450-625): 8.83e-42: 160: 28.33		TMTC3_HUMAN (216-411): 8.03e-13: 72.5: 8.45
+	Hs
		723235 ACHB4_HUMAN (450-626): 2.88e-37: 147: 28.02		TMTC3_HUMAN (216-411): 8.03e-13: 72.5: 8.45
+	Hs
		1057553 ACHD_HUMAN (450-620): 6.79e-27: 116: 17.51		TMTC3_HUMAN (216-411): 8.03e-13: 72.5: 8.45
+	Hs
		1449430 ACHA9_HUMAN (456-621): 1.68e-11: 69: 15.61		KLC4_HUMAN (3-255): 2.23e-21: 98.3: 12.50
+	Hs
		1429716 ACHA9_HUMAN (456-621): 1.68e-11: 69: 15.61		KLC2_HUMAN (3-252): 7.7e-19: 90.6: 13.51