Protein: KLC2
Kinesin light chain 2 (KLC 2)

Gene: KLC2
Organism: Homo sapiens
Interactions: 136
UniProt ID: Q9H0B6

Gene Ontology (top 5):
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005765 - lysosomal membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1060573

KLC1
Kinesin light chain 1

6

16

High-throughput

0.949

High

1429710

KLC4
Kinesin light chain 4

4

17

High-throughput

0.897

High

537877

HSP7C
Heat shock cognate 71 kDa protein

4

7

High-throughput

0.875

High

1242697

KLC3
Kinesin light chain 3

3

18

High-throughput

0.871

High

691415

1433T
14-3-3 protein theta

7

20

High-throughput

0.746

High

730225

1433B
14-3-3 protein beta/alpha

6

20

High-throughput

0.735

High

966856

1433G
14-3-3 protein gamma

6

20

High-throughput

0.735

High

990712

1433Z
14-3-3 protein zeta/delta

6

20

High-throughput

0.734

High

1429720

JIP3
C-Jun-amino-terminal kinase-interacting protein 3

1

13

Small-scale

0.724

High

1049763

1433F
14-3-3 protein eta

5

20

High-throughput

0.716

High

750000

KINH
Kinesin-1 heavy chain

5

20

Small-scale

0.714

High

931101

HSP72
Heat shock-related 70 kDa protein 2

1

7

High-throughput

0.691

High

971982

1433E
14-3-3 protein epsilon

3

8

High-throughput

0.675

High

171810

AZIN1
Antizyme inhibitor 1

3

2

High-throughput

0.667

High

244869

TRAK2
Trafficking kinesin-binding protein 2

3

20

High-throughput

0.667

High

1338950

NUP43
Nucleoporin Nup43

3

12

High-throughput

0.667

High

1389797

DTBP1
Dysbindin

3

2

High-throughput

0.667

High

1429716

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

3

2

High-throughput

0.667

High

1429727

KPTN
KICSTOR complex protein kaptin

3

2

High-throughput

0.667

High

1201741

NADL2
Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2

3

0

High-throughput

0.638

High

252911

EXOC3
Exocyst complex component 3

2

1

High-throughput

0.628

High

335704

MOCS3
Adenylyltransferase and sulfurtransferase MOCS3

2

3

High-throughput

0.628

High

424552

PAI2
Plasminogen activator inhibitor 2

2

1

High-throughput

0.628

High

553762

MYCL
Protein L-Myc

2

9

High-throughput

0.628

High

1384260

SH3K1
SH3 domain-containing kinase-binding protein 1

2

5

High-throughput

0.628

High

1429719

ANC2
Anaphase-promoting complex subunit 2

1

14

High-throughput

0.618

High

730876

1433S
14-3-3 protein sigma

2

20

High-throughput

0.612

High

244185

KIF5C
Kinesin heavy chain isoform 5C

2

20

Small-scale

0.611

High

1087032

KIF5A
Kinesin heavy chain isoform 5A

2

20

Small-scale

0.611

High

1323883

SYNE4
Nesprin-4

3

7

High-throughput

0.609

High

423124

A4
Amyloid-beta precursor protein

2

5

High-throughput

0.602

High

1429537

MIS12
Protein MIS12 homolog

2

0

High-throughput

0.602

High

1429721

TRAK1
Trafficking kinesin-binding protein 1

2

19

High-throughput

0.601

High

845794

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.586

High

108094

G3V5R9
Kinesin light chain

1

15

High-throughput

0.575

High

1429723

COG6
Conserved oligomeric Golgi complex subunit 6

2

2

High-throughput

0.574

High

1324622

RUSC2
AP-4 complex accessory subunit RUSC2

1

3

Small-scale

0.552

High

1209637

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

3

High-throughput

0.536

High

222198

NCK2
Cytoplasmic protein NCK2

1

5

High-throughput

0.536

High

324040

CSTN1
Calsyntenin-1

1

8

High-throughput

0.536

High

347310

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.536

High

361355

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.536

High

445257

S10A6
Protein S100-A6

1

10

High-throughput

0.536

High

463756

LYN
Tyrosine-protein kinase Lyn

1

1

High-throughput

0.536

High

549679

PRPS2
Ribose-phosphate pyrophosphokinase 2

1

3

High-throughput

0.536

High

682605

S100P
Protein S100-P

1

10

High-throughput

0.536

High

789219

NUP62
Nuclear pore glycoprotein p62

1

7

High-throughput

0.536

High

839363

MTOR
Serine/threonine-protein kinase mTOR

1

2

High-throughput

0.536

High

958345

ARP2
Actin-related protein 2

1

5

High-throughput

0.536

High

1091037

BFSP1
Filensin

1

20

High-throughput

0.536

High

1103065

PPIL2
RING-type E3 ubiquitin-protein ligase PPIL2

1

2

High-throughput

0.536

High

1273126

MOB1B
MOB kinase activator 1B

1

2

High-throughput

0.536

High

1289613

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.536

High

1322308

SPART
Spartin

1

10

Small-scale

0.536

High

1357209

BRK1
Protein BRICK1

1

1

High-throughput

0.536

High

1370626

GPKOW
G-patch domain and KOW motifs-containing protein

1

1

High-throughput

0.536

High

1382379

SPSB4
SPRY domain-containing SOCS box protein 4

1

12

High-throughput

0.536

High

1382528

TRI52
E3 ubiquitin-protein ligase TRIM52

1

6

High-throughput

0.536

High

1402669

SMC6
Structural maintenance of chromosomes protein 6

1

2

High-throughput

0.536

High

1429705

RABE2
Rab GTPase-binding effector protein 2

1

4

High-throughput

0.536

High

1429707

CPAP
Centrosomal P4.1-associated protein

1

6

High-throughput

0.536

High

1429708

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.536

High

1429709

DMAP1
DNA methyltransferase 1-associated protein 1

1

2

High-throughput

0.536

High

1429711

ARL8B
ADP-ribosylation factor-like protein 8B

1

1

High-throughput

0.536

High

1429713

ABI2
Abl interactor 2

1

6

High-throughput

0.536

High

1429722

NTNG1
Netrin-G1

1

1

High-throughput

0.536

High

1429724

RT02
Small ribosomal subunit protein uS2m

1

1

High-throughput

0.536

High

1429725

MB212
Protein mab-21-like 2

1

1

High-throughput

0.536

High

1429729

RM42
Large ribosomal subunit protein mL42

1

1

High-throughput

0.536

High

1410938

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

5

Small-scale

0.527

High

1155744

EZH2
Histone-lysine N-methyltransferase EZH2

1

14

High-throughput

0.515

High

158878

AP3D1
AP-3 complex subunit delta-1

1

0

High-throughput

0.513

High

788772

SRP14
Signal recognition particle 14 kDa protein

1

0

High-throughput

0.513

High

1136064

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

1211850

THEM4
Acyl-coenzyme A thioesterase THEM4

1

0

High-throughput

0.513

High

1276038

TPC11
Trafficking protein particle complex subunit 11

1

0

High-throughput

0.513

High

1289037

CATAC
Centrosomal AT-AC splicing factor

1

0

High-throughput

0.513

High

1429706

GEMI7
Gem-associated protein 7

1

0

High-throughput

0.513

High

1429726

TIM8B
Mitochondrial import inner membrane translocase subunit Tim8 B

1

0

High-throughput

0.513

High

1429728

EID1
EP300-interacting inhibitor of differentiation 1

1

0

High-throughput

0.513

High

800092

COIL
Coilin

1

3

High-throughput

0.508

High

1364870

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

1

2

High-throughput

0.508

High

706304

S10A2
Protein S100-A2

1

10

High-throughput

0.489

High

1179852

INSY1
Inhibitory synaptic factor 1

1

1

High-throughput

0.489

High

1400991

ARX
Homeobox protein ARX

1

7

High-throughput

0.489

High

1096634

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

High-throughput

0.486

High

223319

PRC1
Protein regulator of cytokinesis 1

1

2

High-throughput

0.481

High

1402075

TRIB1
Tribbles homolog 1

1

2

Small-scale

0.481

High

1429718

DDX41
Probable ATP-dependent RNA helicase DDX41

1

4

High-throughput

0.481

High

242866

PRKN
E3 ubiquitin-protein ligase parkin

1

14

High-throughput

0.479

High

290147

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

342033

CEP43
Centrosomal protein 43

1

3

High-throughput

0.479

High

412583

NTRK1
High affinity nerve growth factor receptor

1

11

High-throughput

0.479

High

515734

TPC2B
Trafficking protein particle complex subunit 2B

1

2

High-throughput

0.479

High

589640

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.479

High

607091

CEBPB
CCAAT/enhancer-binding protein beta

1

6

High-throughput

0.479

High

765022

CTNB1
Catenin beta-1

1

6

High-throughput

0.479

High

791703

SYUA
Alpha-synuclein

1

2

High-throughput

0.479

High

831398

CCNF
Cyclin-F

1

5

High-throughput

0.479

High

1045751

TF65
Transcription factor p65

1

4

High-throughput

0.479

High

1067700

EP300
Histone acetyltransferase p300

1

6

High-throughput

0.479

High

1121332

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.479

High

1156595

CCDC6
Coiled-coil domain-containing protein 6

1

4

High-throughput

0.479

High

1233470

LTOR1
Ragulator complex protein LAMTOR1

1

1

High-throughput

0.479

High

1251954

LMTK1
Serine/threonine-protein kinase LMTK1

1

17

High-throughput

0.479

High

1255464

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

1291578

HOOK3
Protein Hook homolog 3

1

10

High-throughput

0.479

High

1310873

LMTK2
Serine/threonine-protein kinase LMTK2

1

15

High-throughput

0.479

High

1363840

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

2

High-throughput

0.479

High

1368105

HDAC2
Histone deacetylase 2

1

5

High-throughput

0.479

High

1385387

ARMC5
Armadillo repeat-containing protein 5

1

5

High-throughput

0.479

High

1429703

PKHA4
Pleckstrin homology domain-containing family A member 4

1

12

High-throughput

0.479

High

1429715

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

1429717

HOOK1
Protein Hook homolog 1

1

6

High-throughput

0.479

High

556332

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

898528

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.458

High

1338362

FBX22
F-box only protein 22

1

0

High-throughput

0.458

High

1386781

GCP3
Gamma-tubulin complex component 3

1

0

High-throughput

0.458

High

424265

S10A8
Protein S100-A8

1

10

High-throughput

0.457

High

515656

TPC2A
Trafficking protein particle complex subunit 2

1

2

High-throughput

0.445

High

530356

TAU
Microtubule-associated protein tau

1

13

High-throughput

0.445

High

668231

CXCR2
C-X-C chemokine receptor type 2

1

1

Small-scale

0.445

High

765873

BMI1
Polycomb complex protein BMI-1

1

10

High-throughput

0.445

High

935111

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.445

High

1094415

CSN1
COP9 signalosome complex subunit 1

1

5

High-throughput

0.445

High

1258571

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

6

High-throughput

0.445

High

1353720

MOT10
Monocarboxylate transporter 10

1

1

High-throughput

0.445

High

1429714

S53A1
Solute carrier family 53 member 1

1

2

High-throughput

0.445

High

1053460

FHI1A
FHF complex subunit HOOK-interacting protein 1A

1

10

High-throughput

0.437

High

1219956

FHI2A
FHF complex subunit HOOK interacting protein 2A

1

10

High-throughput

0.437

High

1241953

FBX42
F-box only protein 42

1

7

High-throughput

0.437

High

1290241

FHI2B
FHF complex subunit HOOK-interacting protein 2B

1

10

High-throughput

0.437

High

1429712

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

2

High-throughput

0.437

High

1429704

VIAAT
Vesicular inhibitory amino acid transporter

1

0

High-throughput

0.426

High

1329703

AR6P6
ADP-ribosylation factor-like protein 6-interacting protein 6

1

0

High-throughput

0.279

Low

1385692

ENTR1
Endosome-associated-trafficking regulator 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025