HitPredict

Interactor 1: IMA1 (P52292)
Importin subunit alpha-1 (Karyopherin subunit alpha-2) (RAG cohort protein 1) (SRP1-alpha)
Gene: KPNA2

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 529 Hs			1 2000
+	Hs
		131423 IMA4_HUMAN (4-529): 6.93e-148: 436: 49.06		CHD3_HUMAN (1-2000): 0: 1917: 100.00
+	Hs
		853580 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		CHD3_HUMAN (1-2000): 0: 1917: 100.00
+	Hs
		853286 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		134899 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		238679 IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		168636 IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		853602 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Dm
		283986 O76522_DROME (1-529): 3.96e-136: 405: 47.17		CHDM_DROME (78-1944): 0: 1408: 52.01
+	Mm
		853539 IMA1_MOUSE (1-529): 2.1e-162: 473: 94.52		CHD8_MOUSE (84-1804): 0: 865: 22.94
+	Hs
		853480 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Mm
		192636 IMA4_MOUSE (4-529): 8.91e-149: 438: 49.06		CHD8_MOUSE (84-1804): 0: 865: 22.94
+	Hs
		134969 IMA3_HUMAN (4-529): 5.61e-152: 446: 50.38		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		238743 IMA7_HUMAN (1-528): 1.97e-141: 420: 45.37		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		168673 IMA6_HUMAN (1-528): 9.99e-138: 410: 45.02		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		846725 IMA1_HUMAN (1-529): 6.78e-164: 477: 100.00		SMCA2_HUMAN (73-1644): 0: 718: 20.07
+	Hs
		229344 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Hs
		658643 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		SMCA1_HUMAN (622-1597): 0: 776: 28.08
+	Hs
		846726 IMA5_HUMAN (4-528): 7.39e-133: 398: 44.47		SMCA2_HUMAN (73-1644): 0: 718: 20.07
+	Zm
		11289 A0A1D6FC42_MAIZE (1-529): 3.37e-152: 447: 44.18		A0A1D6IBX9_MAIZE (305-448): 1.39e-11: 72.4: 22.22
+	Zm
		12493 A0A1D6FMC0_MAIZE (1-529): 5.56e-145: 430: 39.69		A0A1D6IBX9_MAIZE (305-448): 1.39e-11: 72.4: 22.22