HitPredict

Interactor 1: T2AG (P52657)
Transcription initiation factor IIA subunit 2 (General transcription factor IIA subunit 2) (TFIIA p12 subunit) (TFIIA-12) (TFIIAS) (Transcription initiation factor IIA gamma chain) (TFIIA-gamma)
Gene: GTF2A2

Interactor 2: TBPL1 (P62380)
TATA box-binding protein-like 1 (TBP-like 1) (21 kDa TBP-like protein) (Second TBP of unique DNA protein) (STUD) (TATA box-binding protein-related factor 2) (TBP-related factor 2) (TBP-like factor) (TBP-related protein)
Gene: TBPL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	1.00	0.855

Property	Details
Experiments	33961781, 17353931, 17643375
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	TBP~TFIIA_gamma_C
Common GO terms	GO:0005672 - transcription factor TFIIA complex GO:0006366 - transcription by RNA polymerase II GO:0016251 - RNA polymerase II general transcription initiation factor activity
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 109 Hs			1 186
+	Hs
		589813 T2AG_HUMAN (1-109): 1.01e-57: 175: 100.00		TBP_HUMAN (2-183): 2.39e-83: 251: 39.67
+	Dm
		589960 T2AG_DROME (1-102): 5.74e-53: 162: 78.64		TBP_DROME (2-184): 4.35e-87: 261: 37.84
+	Dm
		855424 T2AG_DROME (1-102): 5.74e-53: 162: 78.64		Q8T052_DROME (3-184): 6.34e-75: 238: 55.98
+	Sc
		526977 T2AG_YEAST (3-103): 3.42e-41: 133: 36.52		TBP_YEAST (2-183): 5.93e-81: 241: 36.96