Protein: DMC1
Meiotic recombination protein DMC1

Gene: DMC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 65
UniProt ID: P25453

Gene Ontology (top 5):
GO:0000150 - DNA strand exchange activity
GO:0000709 - meiotic joint molecule formation
GO:0000730 - DNA recombinase assembly
GO:0000794 - condensed nuclear chromosome
GO:0003690 - double-stranded DNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

675271

DMC1
Meiotic recombination protein DMC1

7

18

Small-scale

0.958

High

675272

RAD51
DNA repair protein RAD51

3

18

Small-scale

0.840

High

675287

RDH54
DNA repair and recombination protein RDH54

4

18

Small-scale

0.689

High

675282

RAD54
DNA repair and recombination protein RAD54

4

19

Small-scale

0.688

High

675279

MEI5
Meiosis protein 5

2

1

Small-scale

0.644

High

675274

RFA2
Replication factor A protein 2

2

5

Small-scale

0.629

High

675301

ACAC
Acetyl-CoA carboxylase

2

5

Small-scale

0.614

High

675273

MAS5
Mitochondrial protein import protein MAS5

2

5

High-throughput

0.584

High

675300

SAE3
Pachytene arrest protein SAE3

2

0

Small-scale

0.577

High

675289

TEM1
Protein TEM1

2

2

High-throughput

0.539

High

675285

MDJ1
DnaJ homolog 1, mitochondrial

1

7

High-throughput

0.536

High

675306

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.536

High

417036

VDAC1
Non-selective voltage-gated ion channel 1

1

0

High-throughput

0.513

High

675307

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.513

High

675303

ULS1
ATP-dependent helicase ULS1

1

3

Small-scale

0.508

High

675297

MND1
Meiotic nuclear division protein 1

1

5

Small-scale

0.501

High

675298

HOP2
Homologous-pairing protein 2

1

3

Small-scale

0.501

High

366945

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.500

High

486054

TBA1
Tubulin alpha-1 chain

1

4

High-throughput

0.500

High

486413

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.500

High

543955

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.500

High

592043

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.500

High

603415

VATA
V-type proton ATPase catalytic subunit A

1

6

High-throughput

0.500

High

626610

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.500

High

675276

URA7
CTP synthase 1

1

1

High-throughput

0.500

High

675278

PYC2
Pyruvate carboxylase 2

1

4

High-throughput

0.500

High

675283

PRS6B
26S proteasome regulatory subunit 6B homolog

1

2

High-throughput

0.500

High

675286

EF1G2
Elongation factor 1-gamma 2

1

1

High-throughput

0.500

High

675288

YHI0
Putative proline--tRNA ligase YHR020W

1

1

High-throughput

0.500

High

675296

TCPQ
T-complex protein 1 subunit theta

1

3

High-throughput

0.500

High

675302

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.500

High

675281

MRE11
Double-strand break repair protein MRE11

1

0

High-throughput

0.493

High

368324

TRPG
Multifunctional tryptophan biosynthesis protein [Includes: Anthranilate synthase component 2

1

2

High-throughput

0.489

High

439261

PDC1
Pyruvate decarboxylase isozyme 1

1

2

Small-scale

0.481

High

596917

PDC5
Pyruvate decarboxylase isozyme 2

1

2

Small-scale

0.481

High

675291

NDC80
Kinetochore protein NDC80

1

3

Small-scale

0.481

High

408293

GAL1
Galactokinase

1

0

High-throughput

0.479

High

454080

DHE4
NADP-specific glutamate dehydrogenase 1

1

0

High-throughput

0.479

High

675305

APC2
Anaphase-promoting complex subunit 2

1

5

Small-scale

0.464

High

466777

SWI5
Transcriptional factor SWI5

1

0

Small-scale

0.460

High

675294

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.458

High

675295

MAD3
Spindle assembly checkpoint component MAD3

1

0

Small-scale

0.458

High

675304

REC8
Meiotic recombination protein REC8

1

0

Small-scale

0.458

High

367704

ENO1
Enolase 1

1

1

High-throughput

0.457

High

386585

TBB
Tubulin beta chain

1

2

High-throughput

0.457

High

394278

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.457

High

405040

LEU3
3-isopropylmalate dehydrogenase

1

2

High-throughput

0.457

High

456342

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

2

High-throughput

0.457

High

555017

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

575395

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

2

High-throughput

0.457

High

675275

IDH2
Isocitrate dehydrogenase [NAD] subunit 2, mitochondrial

1

1

High-throughput

0.457

High

675277

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

1

High-throughput

0.457

High

675293

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.457

High

510238

HSP77
Import motor subunit, mitochondrial

1

2

High-throughput

0.445

High

526026

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

569381

DPM1
Dolichol-phosphate mannosyltransferase

1

0

High-throughput

0.279

Low

675292

SLM1
Phosphatidylinositol 4,5-bisphosphate-binding protein SLM1

1

0

High-throughput

0.265

Low

572525

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.261

Low

644720

CLH
Clathrin heavy chain

1

0

High-throughput

0.261

Low

675284

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.261

Low

675290

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.261

Low

675280

PT309
Mitochondrial COX1 translation regulator PET309

1

0

Small-scale

0.251

Low

673461

RHEB
GTP-binding protein RHB1

1

0

High-throughput

0.238

Low

675299

YNB3
Putative uncharacterized protein YNL013C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025