Protein: RAD51
DNA repair protein RAD51

Gene: RAD51
Organism: Saccharomyces cerevisiae S288C
Interactions: 87
UniProt ID: P25454

Gene Ontology (top 5):
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0000150 - DNA strand exchange activity
GO:0000228 - nuclear chromosome
GO:0000262 - mitochondrial chromosome
GO:0000709 - meiotic joint molecule formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

675308

RAD51
DNA repair protein RAD51

14

18

Small-scale

0.978

High

675272

DMC1
Meiotic recombination protein DMC1

3

18

Small-scale

0.840

High

448432

RAD52
DNA repair and recombination protein RAD52

34

6

Small-scale

0.770

High

675320

RAD54
DNA repair and recombination protein RAD54

20

19

Small-scale

0.766

High

557671

SRS2
ATP-dependent DNA helicase SRS2

12

4

Small-scale

0.758

High

671479

RAD57
DNA repair protein RAD57

2

18

Small-scale

0.757

High

675332

RAD55
DNA repair protein RAD55

8

1

Small-scale

0.747

High

647705

RFA1
Replication factor A protein 1

5

3

Small-scale

0.714

High

675348

HED1
Meiosis-specific protein HED1

5

0

Small-scale

0.681

High

675340

CSM2
Chromosome segregation in meiosis protein 2

4

1

Small-scale

0.679

High

578923

HSC82
ATP-dependent molecular chaperone HSC82

4

4

High-throughput

0.673

High

392303

HSP82
ATP-dependent molecular chaperone HSP82

4

4

Small-scale

0.672

High

675327

RDH54
DNA repair and recombination protein RDH54

3

18

Small-scale

0.651

High

675355

SMT3
Ubiquitin-like protein SMT3

2

2

Small-scale

0.637

High

399346

CARB
Carbamoyl phosphate synthase arginine-specific large chain

2

4

High-throughput

0.621

High

470472

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

5

High-throughput

0.621

High

644874

RPA2
DNA-directed RNA polymerase I subunit RPA135

2

5

High-throughput

0.621

High

675321

PRS6B
26S proteasome regulatory subunit 6B homolog

2

2

High-throughput

0.621

High

675344

SYEC
Glutamate--tRNA ligase, cytoplasmic

2

1

High-throughput

0.621

High

471374

ARO1
Pentafunctional AROM polypeptide [Includes: 3-dehydroquinate synthase

2

0

High-throughput

0.595

High

675333

FHP
Flavohemoprotein

2

0

High-throughput

0.595

High

675324

SGS1
ATP-dependent helicase SGS1

2

13

Small-scale

0.594

High

675343

GCN20
Protein GCN20

2

1

High-throughput

0.588

High

675315

MCM4
DNA replication licensing factor MCM4

2

1

Small-scale

0.586

High

675356

PSY3
Platinum sensitivity protein 3

2

0

Small-scale

0.569

High

575396

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

2

2

High-throughput

0.567

High

598818

PFKA1
ATP-dependent 6-phosphofructokinase subunit alpha

2

0

High-throughput

0.563

High

675352

BRE1
E3 ubiquitin-protein ligase BRE1

1

6

Small-scale

0.561

High

526027

HSP72
Heat shock protein SSA2

2

4

High-throughput

0.552

High

543956

SSB1
Ribosome-associated molecular chaperone SSB1

2

5

High-throughput

0.552

High

675339

SSB2
Ribosome-associated molecular chaperone SSB2

2

5

High-throughput

0.552

High

675337

RT105
Regulator of Ty1 transposition protein 105

1

0

Small-scale

0.537

High

675338

IMB4
Importin subunit beta-4

2

1

High-throughput

0.537

High

626611

HSP60
Heat shock protein 60, mitochondrial

1

4

High-throughput

0.536

High

675331

MLH1
DNA mismatch repair protein MLH1

1

3

High-throughput

0.536

High

394279

EF1A
Elongation factor 1-alpha

2

1

High-throughput

0.533

High

586432

PCNA
Proliferating cell nuclear antigen

1

1

Small-scale

0.527

High

675313

HRR25
Casein kinase I homolog HRR25

1

0

High-throughput

0.518

High

675349

HMO1
High mobility group protein 1

1

1

High-throughput

0.515

High

675335

SAP1
Protein SAP1

1

5

High-throughput

0.508

High

675345

UBC9
SUMO-conjugating enzyme UBC9

1

5

High-throughput

0.508

High

675351

CST9
Chromosome stability protein 9

1

1

Small-scale

0.508

High

602336

PHO85
Cyclin-dependent protein kinase PHO85

1

2

High-throughput

0.501

High

675310

RFA2
Replication factor A protein 2

1

5

Small-scale

0.501

High

675317

MEI5
Meiosis protein 5

1

1

Small-scale

0.501

High

675316

EF2
Elongation factor 2

1

1

High-throughput

0.489

High

675342

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.489

High

675314

MCM5
Minichromosome maintenance protein 5

1

1

Small-scale

0.481

High

675311

RFA3
Replication factor A protein 3

1

0

Small-scale

0.480

High

675346

H3
Histone H3

1

2

Small-scale

0.479

High

675353

RAD59
DNA repair protein RAD59

1

6

Small-scale

0.479

High

675360

RUVB2
RuvB-like protein 2

1

3

High-throughput

0.479

High

675361

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.479

High

675319

RAD23
UV excision repair protein RAD23

1

1

High-throughput

0.470

High

675326

VRP1
Verprolin

1

1

High-throughput

0.470

High

675354

YP011
Uncharacterized mitochondrial carrier YPR011C

1

3

High-throughput

0.464

High

509423

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

2

High-throughput

0.457

High

555018

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

453444

PYR1
Multifunctional protein URA2

1

2

High-throughput

0.445

High

481501

HSP73
Heat shock protein SSA3

1

4

High-throughput

0.445

High

523179

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

592044

VATB
V-type proton ATPase subunit B

1

4

High-throughput

0.445

High

675309

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.445

High

675318

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

675322

PRS7
26S proteasome regulatory subunit 7 homolog

1

1

High-throughput

0.445

High

675323

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

675325

MDJ1
DnaJ homolog 1, mitochondrial

1

7

High-throughput

0.445

High

675336

HSP7E
Heat shock protein SSC3, mitochondrial

1

2

High-throughput

0.445

High

675358

APC2
Anaphase-promoting complex subunit 2

1

5

Small-scale

0.439

High

368133

THDH
Threonine dehydratase, mitochondrial

2

0

High-throughput

0.324

High

675341

MKT1
Post-transcriptional regulator MKT1

2

0

High-throughput

0.324

High

675347

CLU
Clustered mitochondria protein 1

2

0

High-throughput

0.307

High

675359

AHA1
Hsp90 co-chaperone AHA1

1

0

Small-scale

0.288

High

450531

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.279

Low

554312

HMDH1
3-hydroxy-3-methylglutaryl-coenzyme A reductase 1

1

0

High-throughput

0.279

Low

358974

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

0

High-throughput

0.269

Low

675329

MED6
Mediator of RNA polymerase II transcription subunit 6

1

0

High-throughput

0.269

Low

675350

TRI1
Protein TRI1

1

0

High-throughput

0.265

Low

675334

SAW1
Single-strand annealing weakened protein 1

1

0

Small-scale

0.261

Low

675330

ORC6
Origin recognition complex subunit 6

1

0

Small-scale

0.251

Low

618897

ARF2
ADP-ribosylation factor 2

1

0

High-throughput

0.249

Low

675312

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

675362

YP238
Putative uncharacterized protein YPL238C

1

0

High-throughput

0.238

Low

452714

ADR1
Regulatory protein ADR1

1

0

High-throughput

0.232

Low

675328

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.232

Low

675357

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025