HitPredict

Interactor 1: VAV2 (P52735)
Guanine nucleotide exchange factor VAV2 (VAV-2)
Gene: VAV2

Interactor 2: TRI67 (Q6ZTA4)
Tripartite motif-containing protein 67 (TRIM9-like protein)
Gene: TRIM67

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36215168
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RhoGEF~fn3, SH2~fn3
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 878 Hs			1 783
+	Hs
		1172216 VAV3_HUMAN (1-875): 1.54e-178: 538: 49.61		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170938 PREX1_HUMAN (180-534): 2.34e-69: 253: 24.61		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1016921 AKP13_HUMAN (33-841): 1.1e-67: 248: 10.71		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1171746 ECT2_HUMAN (99-622): 1.95e-67: 243: 13.85		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		200777 ARHG9_HUMAN (161-601): 2.5e-70: 243: 19.82		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1170814 NGEF_HUMAN (41-541): 1.73e-67: 240: 15.12		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		224719 KALRN_HUMAN (164-650): 4.79e-62: 231: 15.81		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		279875 TRIO_HUMAN (187-658): 6.64e-51: 197: 13.25		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1066031 ARHG6_HUMAN (742-874): 2.14e-14: 79.5: 24.81		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1049713 ARHG7_HUMAN (684-877): 7.11e-14: 78: 18.00		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1078848 ITSN1_HUMAN (343-873): 2.52e-12: 73.2: 12.61		TRI67_HUMAN (1-783): 0: 593: 100.00
+	Hs
		1235257 NGEF_HUMAN (41-541): 1.73e-67: 240: 15.12		TRI63_HUMAN (298-505): 1.17e-83: 272: 27.40
+	Hs
		1235266 NGEF_HUMAN (41-541): 1.73e-67: 240: 15.12		TRI55_HUMAN (189-505): 9.32e-81: 270: 19.57
+	Hs
		1318697 ECT2_HUMAN (99-622): 1.95e-67: 243: 13.85		TRIM7_HUMAN (203-762): 1.89e-73: 249: 15.50
+	Hs
		1232422 ECT2_HUMAN (99-622): 1.95e-67: 243: 13.85		CMYA5_HUMAN (262-606): 5.31e-36: 149: 19.32
+	Hs
		1078906 ITSN1_HUMAN (343-873): 2.52e-12: 73.2: 12.61		TRIM5_HUMAN (195-774): 2.68e-77: 260: 13.90
+	Hs
		1066047 ARHG6_HUMAN (742-874): 2.14e-14: 79.5: 24.81		TRI54_HUMAN (198-528): 4.04e-73: 244: 20.71
+	Hs
		537073 ECT2_HUMAN (99-622): 1.95e-67: 243: 13.85		TRI27_HUMAN (105-456): 1.65e-10: 66.3: 14.77
+	Hs
		1318728 ECT2_HUMAN (99-622): 1.95e-67: 243: 13.85		TRIM4_HUMAN (1-123): 1.51e-09: 63.2: 18.70
+	Hs
		584954 GRAP_HUMAN (609-873): 2.81e-20: 92: 24.81		RO52_HUMAN (120-378): 1.33e-12: 72.8: 10.81