Protein: SUV92
Histone-lysine N-methyltransferase SUV39H2 (EC 2.1.1.355) (Histone H3-K9 methyltransferase 2) (H3-K9-HMTase 2) (Lysine N-methyltransferase 1B) (Suppressor of variegation 3-9 homolog 2) (Su(var)3-9 homolog 2)

Gene: SUV92, SUV39H2
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q9H5I1

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

853409

CBX5
Chromobox protein homolog 5

5

20

Small-scale

0.928

High

1014204

CBX1
Chromobox protein homolog 1

4

20

High-throughput

0.903

High

1396305

EHMT2
Histone-lysine N-methyltransferase EHMT2

3

15

High-throughput

0.861

High

1434601

EHMT1
Histone-lysine N-methyltransferase EHMT1

3

14

High-throughput

0.861

High

1097562

CBX3
Chromobox protein homolog 3

2

20

High-throughput

0.789

High

1213589

PHF19
PHD finger protein 19

1

4

High-throughput

0.740

High

1337802

DP13B
DCC-interacting protein 13-beta

5

0

High-throughput

0.689

High

1434489

ZN644
Zinc finger protein 644

3

10

High-throughput

0.667

High

1434610

V9HWG0
Epididymis luminal protein 25

1

20

High-throughput

0.665

High

1434607

MTF2
Metal-response element-binding transcription factor 2

1

4

High-throughput

0.656

High

998807

H31
Histone H3.1

1

20

Small-scale

0.647

High

351405

CBX7
Chromobox protein homolog 7

1

20

Small-scale

0.621

High

1017210

H33
Histone H3.3

1

20

High-throughput

0.618

High

1434602

RASF1
Ras association domain-containing protein 1

2

2

High-throughput

0.603

High

1336476

PNMA1
Paraneoplastic antigen Ma1

2

1

High-throughput

0.579

High

520376

ANDR
Androgen receptor

1

20

Small-scale

0.573

High

848941

MAGAB
Melanoma-associated antigen 11

1

4

Small-scale

0.573

High

1328670

KCD17
BTB/POZ domain-containing protein KCTD17

1

1

High-throughput

0.573

High

1417026

CDCA4
Cell division cycle-associated protein 4

1

1

High-throughput

0.573

High

1434603

ZN212
Zinc finger protein 212

1

5

High-throughput

0.573

High

65165

GG6L9
Golgin subfamily A member 6-like protein 9

2

3

High-throughput

0.553

High

1340349

CEP70
Centrosomal protein of 70 kDa

2

1

High-throughput

0.550

High

1434609

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.549

High

1033230

EWS
RNA-binding protein EWS

1

2

High-throughput

0.541

High

270847

ROCK2
Rho-associated protein kinase 2

1

3

High-throughput

0.536

High

899582

TCPD
T-complex protein 1 subunit delta

1

9

High-throughput

0.536

High

1134727

NUMA1
Nuclear mitotic apparatus protein 1

1

5

High-throughput

0.536

High

1410595

TBA1C
Tubulin alpha-1C chain

1

2

High-throughput

0.536

High

1348606

KLDC4
Kelch domain-containing protein 4

1

4

High-throughput

0.523

High

423703

ARGI1
Arginase-1

1

0

High-throughput

0.513

High

1400390

PUS7
Pseudouridylate synthase 7 homolog

1

0

High-throughput

0.513

High

245739

GANP
Germinal-center associated nuclear protein

1

1

High-throughput

0.508

High

345003

WIZ
Protein Wiz

1

9

High-throughput

0.508

High

711414

SHC1
SHC-transforming protein 1

1

6

High-throughput

0.508

High

944743

KLF3
Krueppel-like factor 3

1

18

High-throughput

0.508

High

1036550

ID2
DNA-binding protein inhibitor ID-2

1

2

High-throughput

0.508

High

1229228

ZNF57
Zinc finger protein 57

1

2

High-throughput

0.508

High

1331735

ZN557
Zinc finger protein 557

1

4

High-throughput

0.508

High

1348503

LNX1
E3 ubiquitin-protein ligase LNX

1

3

High-throughput

0.508

High

610891

TCPA
T-complex protein 1 subunit alpha

1

10

High-throughput

0.489

High

821573

TCPZ
T-complex protein 1 subunit zeta

1

9

High-throughput

0.489

High

876170

TCPE
T-complex protein 1 subunit epsilon

1

12

High-throughput

0.489

High

882161

TCPG
T-complex protein 1 subunit gamma

1

12

High-throughput

0.489

High

899235

TCPQ
T-complex protein 1 subunit theta

1

14

High-throughput

0.489

High

1407571

TCPH
T-complex protein 1 subunit eta

1

12

High-throughput

0.489

High

1431832

SLK
STE20-like serine/threonine-protein kinase

1

6

High-throughput

0.489

High

1434600

SH24A
SH2 domain-containing protein 4A

1

6

High-throughput

0.489

High

1212465

LRIF1
Ligand-dependent nuclear receptor-interacting factor 1

1

0

High-throughput

0.486

High

1312604

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.486

High

1392621

SNF8
Vacuolar-sorting protein SNF8

1

0

High-throughput

0.486

High

1400865

RAB3I
Rab-3A-interacting protein

1

0

High-throughput

0.486

High

1431035

RPC6
DNA-directed RNA polymerase III subunit RPC6

1

0

High-throughput

0.486

High

1431863

GO45
Golgin-45

1

0

High-throughput

0.486

High

362377

ABL1
Tyrosine-protein kinase ABL1

1

2

High-throughput

0.479

High

440727

FYN
Tyrosine-protein kinase Fyn

1

2

High-throughput

0.479

High

594102

NCK1
SH2/SH3 adapter protein NCK1

1

6

High-throughput

0.479

High

699858

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

1

High-throughput

0.479

High

855754

CRK
Adapter molecule crk

1

5

High-throughput

0.479

High

987940

GRB2
Growth factor receptor-bound protein 2

1

6

High-throughput

0.479

High

1406692

SMAD5
Mothers against decapentaplegic homolog 5

1

6

Small-scale

0.479

High

63318

ODAD3
Outer dynein arm-docking complex subunit 3

1

2

High-throughput

0.464

High

618737

ML12A
Myosin regulatory light chain 12A

1

2

High-throughput

0.464

High

1193147

CP100
Cilia- and flagella-associated protein 100

1

1

High-throughput

0.464

High

1240285

CH074
Uncharacterized protein C8orf74

1

1

High-throughput

0.464

High

1408536

AKAP9
A-kinase anchor protein 9

1

4

High-throughput

0.464

High

822864

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.460

High

1154295

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

3

High-throughput

0.457

High

1434604

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.438

High

227132

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.437

High

320412

SASH1
SAM and SH3 domain-containing protein 1

1

0

Small-scale

0.426

High

1434605

AP4E1
AP-4 complex subunit epsilon-1

3

0

High-throughput

0.347

High

125853

AP4M1
AP-4 complex subunit mu-1

2

0

High-throughput

0.328

High

1434608

AP4S1
AP-4 complex subunit sigma-1

2

0

High-throughput

0.328

High

649775

SPR2E
Small proline-rich protein 2E

1

0

High-throughput

0.279

Low

984660

RL39
Large ribosomal subunit protein eL39

1

0

High-throughput

0.279

Low

1201061

ACTBL
Beta-actin-like protein 2

1

0

High-throughput

0.279

Low

1328125

TTC9C
Tetratricopeptide repeat protein 9C

1

0

High-throughput

0.279

Low

1430305

GATA
Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial

1

0

High-throughput

0.279

Low

1434606

CHM2B
Charged multivesicular body protein 2b

1

0

High-throughput

0.279

Low

143919

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.265

Low

337236

LCA5L
Lebercilin-like protein

1

0

High-throughput

0.265

Low

1337369

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

1

0

High-throughput

0.265

Low

619109

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025