HitPredict

Interactor 1: VPS4 (P52917)
Vacuolar protein sorting-associated protein 4 (DOA4-independent degradation protein 6) (Protein END13) (Vacuolar protein-targeting protein 10)
Gene: VPS4

Interactor 2: VPS20 (Q04272)
Vacuolar protein sorting-associated protein 20 (Amino acid sensor-independent protein 10) (Charged multivesicular body protein 6) (ESCRT-III complex subunit VPS20) (Vacuolar protein-targeting protein 20)
Gene: VPS20

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.60 0.752

The method score is based on:

Property Details
Experiments 12953057, 17408385, 19591838, 18194652, 24711499, 16704411, 18266866, 22875988
Identification Methods affinity chromatography technology, two hybrid, pull down
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0015031 - protein transport
GO:0032511 - late endosome to vacuole transport via multivesicular body sorting pathway
GO:0045324 - late endosome to vacuole transport
and 1 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 437
Sc

1 221
+ At
+ At
+ Zm
+ Hs
+ Hs
+ Hs
+ Sc
+ Hs
+ Dm
+ Dm
+ Hs
+ At
+ At
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024