Protein: NOTC4
Neurogenic locus notch homolog protein 4 (Notch 4) (hNotch4) [Cleaved into: Notch 4 extracellular truncation; Notch 4 intracellular domain]

Gene: NOTC4, NOTCH4
Organism: Homo sapiens
Interactions: 14
UniProt ID: Q99466

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000139 - Golgi membrane
GO:0000987 - cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001554 - luteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1365151

MAML1
Mastermind-like protein 1

1

12

Small-scale

0.647

High

1404626

EGFL7
Epidermal growth factor-like protein 7

1

19

Small-scale

0.621

High

414470

P53
Cellular tumor antigen p53

1

7

Small-scale

0.618

High

1404627

TRRAP
Transformation/transcription domain-associated protein

1

4

High-throughput

0.618

High

1147108

ELOC
Elongin-C

1

0

Small-scale

0.527

High

1014593

SMAD3
Mothers against decapentaplegic homolog 3

1

12

Small-scale

0.515

High

1106677

SMAD4
Mothers against decapentaplegic homolog 4

1

12

Small-scale

0.515

High

1153887

SMAD2
Mothers against decapentaplegic homolog 2

1

12

Small-scale

0.515

High

422956

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.515

High

989088

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.501

High

521880

H14
Histone H1.4

1

1

High-throughput

0.479

High

1028350

MDM2
E3 ubiquitin-protein ligase Mdm2

1

2

Small-scale

0.479

High

1131107

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

12

Small-scale

0.479

High

1404625

AFF4
AF4/FMR2 family member 4

1

10

High-throughput

0.479

High


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Last updated: 11Aug2025