HitPredict

Interactor 1: PPP5 (P53041)
Serine/threonine-protein phosphatase 5 (PP5) (EC 3.1.3.16) (Protein phosphatase T) (PP-T) (PPT)
Gene: PPP5C

Interactor 2: CHRD1 (Q9UHD1)
Cysteine and histidine-rich domain-containing protein 1 (CHORD domain-containing protein 1) (CHORD-containing protein 1) (CHP-1) (Protein morgana)
Gene: CHORDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	23414517, 25036637
Identification Methods	two hybrid, affinity chromatography technology, two hybrid fragment pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0043531 - ADP binding GO:0051879 - Hsp90 protein binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 499 Hs			1 332
+	Mm
		1141238 PPP5_MOUSE (1-499): 0: 571: 97.80		CHRD1_MOUSE (1-328): 5.56e-174: 487: 96.34
+	Mm
		1141237 PPP5_MOUSE (1-499): 0: 571: 97.80		SGT1_MOUSE (173-332): 1.8e-51: 175: 22.75
+	Hs
		858686 PPP5_HUMAN (1-499): 0: 575: 100.00		SGT1_HUMAN (173-332): 1.99e-46: 162: 18.14