HitPredict

Interactor 1: NEDD4 (P46934)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (Cell proliferation-inducing gene 53 protein) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: TBB8 (Q3ZCM7)
Tubulin beta-8 chain (Tubulin beta 8 class VIII)
Gene: TUBB8

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37863970
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1319 Hs			1 444
+	Hs
		457298 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		861559 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		861754 NEDD4_HUMAN (1-1319): 0: 1940: 100.00		TBB2B_HUMAN (1-430): 0: 719: 90.23
+	Hs
		457523 HUWE1_HUMAN (799-1317): 4.45e-169: 562: 35.32		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		997401 HUWE1_HUMAN (799-1317): 4.45e-169: 562: 35.32		TBB4B_HUMAN (1-427): 0: 719: 91.10
+	Hs
		1118511 HUWE1_HUMAN (799-1317): 4.45e-169: 562: 35.32		TBB2A_HUMAN (1-430): 0: 716: 90.00
+	Dm
		94233 D5SHR3_DROME (898-1316): 2.02e-180: 541: 45.99		TBB1_DROME (1-429): 0: 719: 90.68
+	Dm
		1174639 Q9W325_DROME (899-1316): 7.88e-180: 540: 46.10		TBB1_DROME (1-429): 0: 719: 90.68
+	Hs
		131671 WWP2_HUMAN (461-799): 1.62e-40: 164: 18.79		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		132016 WWP2_HUMAN (461-799): 1.62e-40: 164: 18.79		TBB3_HUMAN (1-442): 0: 719: 86.43
+	Hs
		457720 SMUF1_HUMAN (483-719): 1.25e-23: 110: 15.71		TBB5_HUMAN (1-429): 0: 720: 89.74
+	Hs
		997523 SMUF1_HUMAN (483-719): 1.25e-23: 110: 15.71		TBB4B_HUMAN (1-427): 0: 719: 91.10