HitPredict

Interactor 1: NEDD4 (P46935)
E3 ubiquitin-protein ligase NEDD4 (EC 2.3.2.26) (HECT-type E3 ubiquitin transferase NEDD4) (Neural precursor cell expressed developmentally down-regulated protein 4) (NEDD-4)
Gene: NEDD4

Interactor 2: DLG3 (P70175)
Disks large homolog 3 (Synapse-associated protein 102) (SAP-102) (SAP102)
Gene: DLG3

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	21920314
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C2~SH3_1
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0098978 - glutamatergic synapse
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 887 Mm			1 849
+	Hs
		1368713 NED4L_HUMAN (70-887): 0: 778: 56.22		DLG3_HUMAN (1-849): 0: 678: 95.52
+	Mm
		97734 E9PXB7_MOUSE (172-887): 0: 673: 56.84		DLG3_MOUSE (1-849): 0: 705: 100.00
+	Mm
		1223651 NED4L_MOUSE (39-887): 0: 781: 54.62		DLG4_MOUSE (104-849): 0: 573: 63.55
+	Mm
		97740 E9PXB7_MOUSE (172-887): 0: 673: 56.84		DLG4_MOUSE (104-849): 0: 573: 63.55
+	Hs
		1091527 HUWE1_HUMAN (161-885): 1.37e-178: 575: 28.80		DLG1_HUMAN (4-849): 0: 583: 62.94
+	Hs
		861680 NEDD4_HUMAN (157-887): 0: 735: 79.83		PALS1_HUMAN (2-256): 8.59e-15: 80.6: 12.89
+	Hs
		1368728 HECW2_HUMAN (13-511): 4.48e-19: 95.3: 12.23		DLG3_HUMAN (1-849): 0: 678: 95.52
+	Hs
		1260704 HECW1_HUMAN (7-396): 2.2e-18: 93: 13.69		DLG3_HUMAN (1-849): 0: 678: 95.52
+	Hs
		132160 WWP2_HUMAN (75-884): 0: 681: 33.33		PALS1_HUMAN (2-256): 8.59e-15: 80.6: 12.89
+	Hs
		1325311 WWP1_HUMAN (65-884): 0: 674: 31.17		PALS1_HUMAN (2-256): 8.59e-15: 80.6: 12.89