HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: SRSF6 (Q13247)
Serine/arginine-rich splicing factor 6 (Pre-mRNA-splicing factor SRP55) (Splicing factor, arginine/serine-rich 6)
Gene: SRSF6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25796446
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0010837 - regulation of keratinocyte proliferation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 504 Hs			1 344
+	Hs
		131986 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		132005 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		SRSF5_HUMAN (2-180): 3.8e-46: 160: 64.25
+	Hs
		1061163 SMUF1_HUMAN (55-504): 1.17e-109: 344: 18.62		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		132006 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		SRSF6_HUMAN (1-322): 1.01e-43: 155: 100.00
+	Hs
		1061140 WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		1099245 WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63		SRSF5_HUMAN (2-180): 3.8e-46: 160: 64.25
+	Hs
		132010 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		PABP4_HUMAN (105-191): 8.58e-13: 71.1: 22.83
+	Hs
		132338 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		RBM28_HUMAN (4-248): 1.81e-12: 70.3: 14.61
+	Hs
		131699 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		PABP1_HUMAN (100-191): 9.12e-12: 68: 19.59
+	Hs
		131953 WWP2_HUMAN (12-504): 1.09e-117: 368: 16.54		SRSF3_HUMAN (3-78): 2.42e-09: 57.4: 46.84
+	Hs
		550415 ITCH_HUMAN (3-504): 6.65e-111: 351: 15.47		PABP1_HUMAN (100-191): 9.12e-12: 68: 19.59
+	Hs
		550167 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		PABP1_HUMAN (100-191): 9.12e-12: 68: 19.59
+	Hs
		862453 YAP1_HUMAN (51-504): 2.56e-112: 343: 100.00		PABP3_HUMAN (100-191): 6.3e-11: 65.3: 19.59
+	Sc
		815541 RSP5_YEAST (3-504): 1.28e-97: 314: 15.25		NOP3_YEAST (3-326): 1.2e-19: 91.2: 19.94
+	Hs
		1016606 WWP1_HUMAN (4-504): 4.94e-105: 336: 14.63		SRSF3_HUMAN (3-78): 2.42e-09: 57.4: 46.84
+	Hs
		1061040 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		SRSF1_HUMAN (3-188): 3.03e-54: 180: 36.65
+	Hs
		1280467 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		RBM4_HUMAN (1-343): 1.67e-48: 168: 17.05
+	Hs
		1099141 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		SRSF5_HUMAN (2-180): 3.8e-46: 160: 64.25
+	Sc
		403427 PRP40_YEAST (177-503): 2.01e-52: 188: 12.87		PABP_YEAST (3-190): 1.08e-31: 126: 17.50
+	Hs
		1016494 HUWE1_HUMAN (76-504): 3.07e-59: 213: 10.09		SRSF3_HUMAN (3-78): 2.42e-09: 57.4: 46.84