HitPredict

Interactor 1: RP3A (P47708)
Rabphilin-3A (Exophilin-1)
Gene: Rph3a

Interactor 2: RAB3A (P63011)
Ras-related protein Rab-3A (EC 3.6.5.2)
Gene: RAB3A

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.904

Property	Details
Experiments	12578829, 15099020, 11773082, 10707984, 14722103
Identification Methods	affinity chromatography technology, coimmunoprecipitation, two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FYVE_2~Ras
Common GO terms	GO:0030672 - synaptic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 681 Mm			1 220
+	Mm
		866420 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3B_MOUSE (1-220): 1.02e-106: 307: 78.18
+	Mm
		866413 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3C_MOUSE (1-220): 2.23e-90: 266: 83.18
+	Mm
		770469 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB3D_MOUSE (1-220): 7.97e-85: 252: 75.91
+	Mm
		866412 RP3A_MOUSE (1-681): 0: 642: 100.00		RAB8A_MOUSE (15-219): 2.52e-82: 245: 48.29
+	Rn
		866423 RP3A_RAT (1-681): 0: 626: 97.37		RAB3A_RAT (1-220): 4.26e-86: 255: 100.00
+	Hs
		630670 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB3B_HUMAN (1-220): 8.34e-89: 262: 77.27
+	Hs
		630450 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB3A_HUMAN (1-220): 8.21e-86: 254: 99.09
+	Hs
		956029 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB8A_HUMAN (15-218): 1.47e-82: 246: 48.53
+	Hs
		1370785 RP3A_HUMAN (1-681): 0: 591: 85.71		RAB8B_HUMAN (15-219): 2.46e-82: 245: 46.34
+	Hs
		630605 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3B_HUMAN (1-220): 8.34e-89: 262: 77.27
+	Hs
		630433 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3A_HUMAN (1-220): 8.21e-86: 254: 99.09
+	Hs
		630588 SYTL5_HUMAN (46-680): 2.16e-117: 369: 20.19		RAB3B_HUMAN (1-220): 8.34e-89: 262: 77.27
+	Hs
		976477 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RB11A_HUMAN (12-219): 1.92e-83: 248: 34.27
+	Hs
		343187 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB3D_HUMAN (1-220): 1.71e-82: 246: 77.27
+	Hs
		955988 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB8A_HUMAN (15-218): 1.47e-82: 246: 48.53
+	Hs
		1370773 SYTL4_HUMAN (46-673): 2.5e-123: 383: 21.88		RAB8B_HUMAN (15-219): 2.46e-82: 245: 46.34
+	Mm
		989215 SYTL4_MOUSE (46-673): 2.72e-119: 373: 20.76		RAB3A_MOUSE (1-220): 4.26e-86: 255: 100.00
+	Hs
		630431 SYTL5_HUMAN (46-680): 2.16e-117: 369: 20.19		RAB3A_HUMAN (1-220): 8.21e-86: 254: 99.09
+	Mm
		937173 SYTL4_MOUSE (46-673): 2.72e-119: 373: 20.76		RAB8A_MOUSE (15-219): 2.52e-82: 245: 48.29
+	Hs
		976443 SYTL5_HUMAN (46-680): 2.16e-117: 369: 20.19		RB11A_HUMAN (12-219): 1.92e-83: 248: 34.27