Interactor 1: RAB8A (P61006)
Ras-related protein Rab-8A (EC 3.6.5.2) (Oncogene c-mel)
Gene: RAB8A

Interactor 2: SYTL4 (Q96C24)
Synaptotagmin-like protein 4 (Exophilin-2) (Granuphilin)
Gene: SYTL4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.970

The method score is based on:

Property Details
Experiments 24700782, 26553929, 12590134, 12176990, 11773082, 23140275, 40437099, 26824392, 29125462
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE_2~Ras
Common GO terms GO:0005768 - endosome
GO:0005886 - plasma membrane
GO:0006887 - exocytosis
GO:0031267 - small GTPase binding
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 207
Hs

1 671
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Service provided by Combinatics, Japan

Last updated: 11Aug2025