HitPredict

Interactor 1: BLM (P54132)
RecQ-like DNA helicase BLM (EC 5.6.2.4) (Bloom syndrome protein) (DNA 3'-5' helicase BLM) (DNA helicase, RecQ-like type 2) (RecQ2) (RecQ protein-like 3)
Gene: BLM

Interactor 2: FANCM (Q8IYD8)
Fanconi anemia group M protein (Protein FACM) (EC 3.6.4.13) (ATP-dependent RNA helicase FANCM) (Fanconi anemia-associated polypeptide of 250 kDa) (FAAP250) (Protein Hef ortholog)
Gene: FANCM

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.915

The method score is based on:

Property Details
Experiments 23509288, 24699063, 20347428, 20064461, 16116422
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~DEAD, DEAD~Helicase_C, Helicase_C~Helicase_C, DEAD~HRDC, HRDC~Helicase_C, DEAD~RecQ_Zn_bind, Helicase_C~RecQ_Zn_bind, Helicase_C~RQC
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0009378 - four-way junction helicase activity
and 3 others

more...
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 1417
Hs

1 2048
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+ Sc
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Last updated: 15 Jul 2024