Protein: MTR1L
Melatonin-related receptor (G protein-coupled receptor 50) (H9) [Cleaved into: C-terminal domain]

Gene: MTR1L, GPR50
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q13585

Gene Ontology (top 5):
GO:0004930 - G protein-coupled receptor activity
GO:0005654 - nucleoplasm
GO:0005886 - plasma membrane
GO:0007186 - G protein-coupled receptor signaling pathway
GO:0007267 - cell-cell signaling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

406883

MAS
Proto-oncogene Mas

2

16

High-throughput

0.811

High

702773

5HT2C
5-hydroxytryptamine receptor 2C

2

18

High-throughput

0.811

High

720606

GRPR
Gastrin-releasing peptide receptor

2

19

High-throughput

0.811

High

1111502

MTR1L
Melatonin-related receptor

1

16

Small-scale

0.747

High

133250

P2Y10
Putative P2Y purinoceptor 10

1

16

High-throughput

0.691

High

210390

MTLR
Motilin receptor

1

17

High-throughput

0.691

High

640386

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

17

High-throughput

0.691

High

669223

NK1R
Substance-P receptor

1

19

High-throughput

0.691

High

723684

NTR1
Neurotensin receptor type 1

1

17

High-throughput

0.691

High

867616

GPR12
G-protein coupled receptor 12

1

18

High-throughput

0.691

High

1111512

LPAR1
Lysophosphatidic acid receptor 1

1

18

High-throughput

0.691

High

1111516

GPR21
Probable G-protein coupled receptor 21

1

17

High-throughput

0.691

High

989839

GNAI1
Guanine nucleotide-binding protein G(i) subunit alpha-1

1

20

Small-scale

0.665

High

882483

ARRB1
Beta-arrestin-1

1

9

Small-scale

0.647

High

1111522

IPPK
Inositol-pentakisphosphate 2-kinase

2

1

High-throughput

0.628

High

1111526

CLC2D
C-type lectin domain family 2 member D

2

6

High-throughput

0.628

High

869733

MTR1A
Melatonin receptor type 1A

1

19

Small-scale

0.618

High

880914

MTR1B
Melatonin receptor type 1B

1

19

Small-scale

0.618

High

520836

HLAC
HLA class I histocompatibility antigen, C alpha chain

2

2

High-throughput

0.611

High

1111511

TM171
Transmembrane protein 171

3

1

High-throughput

0.609

High

1111505

ZN572
Zinc finger protein 572

1

1

High-throughput

0.573

High

438881

CD1A
T-cell surface glycoprotein CD1a

1

4

High-throughput

0.536

High

443780

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

7

High-throughput

0.536

High

463956

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

7

High-throughput

0.536

High

622609

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

3

High-throughput

0.536

High

688557

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

6

High-throughput

0.536

High

688662

NKG2C
NKG2-C type II integral membrane protein

1

6

High-throughput

0.536

High

760439

SDC2
Syndecan-2

1

1

High-throughput

0.536

High

800290

INGR2
Interferon gamma receptor 2

1

4

High-throughput

0.536

High

867960

GLR
Glucagon receptor

1

6

High-throughput

0.536

High

1042742

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

6

High-throughput

0.536

High

1111506

INLR1
Interferon lambda receptor 1

1

3

High-throughput

0.536

High

1111507

AGRG5
Adhesion G-protein coupled receptor G5

1

8

High-throughput

0.536

High

1111508

AGRG2
Adhesion G-protein coupled receptor G2

1

8

High-throughput

0.536

High

1111518

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

1111519

S22A4
Solute carrier family 22 member 4

1

2

High-throughput

0.536

High

1111520

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1111527

ALK
ALK tyrosine kinase receptor

1

3

High-throughput

0.536

High

1111528

PCDAC
Protocadherin alpha-12

1

1

High-throughput

0.536

High

1111529

PCDA8
Protocadherin alpha-8

1

1

High-throughput

0.536

High

260754

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.513

High

1111503

H2B2E
Histone H2B type 2-E

1

0

High-throughput

0.493

High

997322

TBB4B
Tubulin beta-4B chain

1

6

High-throughput

0.489

High

1085316

SCAP
Sterol regulatory element-binding protein cleavage-activating protein

1

2

High-throughput

0.489

High

1111514

RUSF1
RUS family member 1

1

2

High-throughput

0.489

High

1111517

IFT27
Intraflagellar transport protein 27 homolog

1

5

High-throughput

0.489

High

1111524

EVA1B
Protein eva-1 homolog B

1

1

High-throughput

0.489

High

1111525

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

1

High-throughput

0.489

High

373915

RASN
GTPase NRas

1

10

High-throughput

0.479

High

375495

RASK
GTPase KRas

1

12

High-throughput

0.479

High

1008429

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

2

Small-scale

0.479

High

1111513

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

125442

LEG9
Galectin-9

1

3

High-throughput

0.437

High

293660

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

391697

MT2
Metallothionein-2

1

1

Small-scale

0.437

High

415119

MT1A
Metallothionein-1A

1

1

Small-scale

0.437

High

1111509

TOR2X
Prosalusin

1

1

High-throughput

0.437

High

1111504

TOR2A
Torsin-2A

1

2

High-throughput

0.407

High

1111515

MR1L1
MORF4 family-associated protein 1-like 1

1

0

High-throughput

0.279

Low

1111521

G3ST2
Galactose-3-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

1111523

CHODL
Chondrolectin

1

0

High-throughput

0.279

Low

1111510

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025