HitPredict - High confidence protein-protein interactions

Method score	Annotation score	Interaction score
0.93	1.00	0.965

Method score

Annotation score

Interaction score

0.93

1.00

0.965

Property	Details
Experiments	24895130, 9130722, 20811636, 19487455, 21044950, 9391075, 11701125
Identification Methods	pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, bimolecular fluorescence complementation
Interaction Type	direct interaction, physical association

Property

Details

Experiments

24895130, 9130722, 20811636, 19487455, 21044950, 9391075, 11701125

Identification Methods

pull down, two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, bimolecular fluorescence complementation

Interaction Type

direct interaction, physical association

Property	Details
Interacting Pfam domains	Myb_DNA-binding~Myb_DNA-binding, TRF~TRF
Common GO terms	GO:0000723 - telomere maintenance GO:0000781 - chromosome, telomeric region GO:0000783 - nuclear telomere cap complex GO:0001650 - fibrillar center GO:0003677 - DNA binding and 33 others more... GO:0003691 - double-stranded telomeric DNA binding GO:0003720 - telomerase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005730 - nucleolus GO:0005737 - cytoplasm GO:0005819 - spindle GO:0007004 - telomere maintenance via telomerase GO:0008017 - microtubule binding GO:0008156 - negative regulation of DNA replication GO:0008301 - DNA binding, bending GO:0016233 - telomere capping GO:0016604 - nuclear body GO:0032206 - positive regulation of telomere maintenance GO:0032211 - negative regulation of telomere maintenance via telomerase GO:0032214 - negative regulation of telomere maintenance via semi-conservative replication GO:0042162 - telomeric DNA binding GO:0042803 - protein homodimerization activity GO:0045141 - meiotic telomere clustering GO:0051301 - cell division GO:0051974 - negative regulation of telomerase activity GO:0061820 - telomeric D-loop disassembly GO:0070187 - shelterin complex GO:0071532 - ankyrin repeat binding GO:0090656 - t-circle formation GO:0098505 - G-rich strand telomeric DNA binding GO:1904357 - negative regulation of telomere maintenance via telomere lengthening GO:1904792 - positive regulation of shelterin complex assembly GO:1904850 - negative regulation of establishment of protein localization to telomere GO:1904911 - negative regulation of establishment of RNA localization to telomere GO:1904914 - negative regulation of establishment of protein-containing complex localization to telomere GO:1905778 - negative regulation of exonuclease activity GO:1905839 - negative regulation of telomeric D-loop disassembly
Homologous interactions	11