HitPredict

Interactor 1: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Interactor 2: ZRAN1 (Q9UGI0)
Ubiquitin thioesterase ZRANB1 (EC 3.4.19.12) (TRAF-binding domain-containing protein) (hTrabid) (Zinc finger Ran-binding domain-containing protein 1)
Gene: ZRANB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35944360
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	OTU~ubiquitin, ubiquitin~zf-RanBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031593 - polyubiquitin modification-dependent protein binding
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 409 Hs			1 708
+	Hs
		1354853 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Mm
		476855 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		ZRAN1_MOUSE (1-697): 0: 989: 99.28
+	Hs
		924207 RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67		ZRAN1_HUMAN (1-697): 0: 987: 100.00
+	Hs
		1151639 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Hs
		599640 RD23A_HUMAN (1-409): 9.12e-94: 287: 56.72		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Hs
		475060 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		OTU7B_HUMAN (322-701): 2.32e-127: 400: 25.54
+	Mm
		70741 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		OTU7B_MOUSE (322-701): 5.79e-124: 391: 25.78
+	Hs
		599749 UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Mm
		476820 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		TNAP3_MOUSE (392-651): 2.36e-92: 306: 36.10
+	Hs
		474920 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		TNAP3_HUMAN (392-651): 2.48e-93: 308: 35.74
+	Mm
		476959 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		RNF31_MOUSE (8-410): 2.07e-87: 298: 14.99
+	Hs
		475133 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		RNF31_HUMAN (29-410): 7.77e-78: 271: 15.73
+	Hs
		275512 UBQL2_HUMAN (1-364): 5.93e-51: 182: 13.68		CAN15_HUMAN (76-256): 3.1e-11: 69.2: 18.85
+	Mm
		477032 UBC_MOUSE (1-118): 1.78e-32: 131: 21.67		CAN15_MOUSE (76-256): 9.79e-12: 70.8: 19.15
+	Hs
		275486 UBB_HUMAN (1-79): 1.99e-32: 123: 30.38		CAN15_HUMAN (76-256): 3.1e-11: 69.2: 18.85
+	Dm
		574856 RL40_DROME (1-84): 1.42e-15: 74.6: 29.76		TRBID_DROME (2-140): 2.6e-16: 85: 28.48