HitPredict

Interactor 1: EPHB4 (P54760)
Ephrin type-B receptor 4 (EC 2.7.10.1) (Hepatoma transmembrane kinase) (Tyrosine-protein kinase TYRO11)
Gene: EPHB4

Interactor 2: TBA1B (P68363)
Tubulin alpha-1B chain (EC 3.6.5.-) (Alpha-tubulin ubiquitous) (Tubulin K-alpha-1) (Tubulin alpha-ubiquitous chain) [Cleaved into: Detyrosinated tubulin alpha-1B chain]
Gene: TUBA1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	36736316
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 987 Hs			1 451
+	Hs
		665575 EPHB2_HUMAN (17-974): 0: 1118: 55.64		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Hs
		933452 EPHA7_HUMAN (3-981): 0: 1100: 48.64		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		1072528 EPHA7_HUMAN (3-981): 0: 1100: 48.64		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		428222 EPHA7_HUMAN (3-981): 0: 1100: 48.64		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		428109 EPHA4_HUMAN (3-981): 0: 1093: 49.70		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		872631 EPHA4_HUMAN (3-981): 0: 1093: 49.70		TBB4B_HUMAN (1-437): 0: 697: 40.96
+	Hs
		665203 EPHA2_HUMAN (15-974): 0: 1016: 44.82		TBA1B_HUMAN (1-440): 0: 717: 100.00
+	Rn
		544865 INSR_RAT (380-879): 6.3e-136: 444: 30.43		TBA4A_RAT (1-450): 0: 719: 96.44
+	Hs
		411416 INSR_HUMAN (380-879): 9.63e-136: 443: 29.65		TBA1A_HUMAN (1-440): 0: 715: 99.55
+	Hs
		435607 IGF1R_HUMAN (390-876): 1.79e-133: 437: 28.00		TBA4A_HUMAN (1-450): 0: 719: 96.44
+	Hs
		411272 INSR_HUMAN (380-879): 9.63e-136: 443: 29.65		TBB5_HUMAN (1-439): 0: 699: 41.23
+	Hs
		983628 FAK1_HUMAN (595-878): 1.01e-61: 230: 41.55		TBA1A_HUMAN (1-440): 0: 715: 99.55