Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: DERL1 (Q9BUN8)
Derlin-1 (Degradation in endoplasmic reticulum protein 1) (DERtrin-1) (Der1-like protein 1)
Gene: DERL1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 27714797, 29599191, 29540532, 18199748, 34739333, 17872946, 35961308, 36300783, 16289116, 16186510, 22119785, 28137758, 34079125, 16186509, 21909096, 16901789
Identification Methods unspecified method, x-ray crystallography, affinity chromatography technology, pull down, proximity labelling technology, anti bait coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0030968 - endoplasmic reticulum unfolded protein response
GO:0030970 - retrograde protein transport, ER to cytosol
GO:0031625 - ubiquitin protein ligase binding
and 7 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 806
Hs

1 251
+ Hs
+ Mm
+ Dm
+ Sc
+ Sc

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Last updated: 15 Jul 2024