HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein deacylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	26496610, 28514442, 31980649, 33961781, unassigned2173
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 482
+	Hs
		876098 TCPE_HUMAN (1-541): 0: 637: 100.00		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		881911 TCPG_HUMAN (14-540): 0: 574: 33.15		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		1110033 TCPH_HUMAN (12-539): 0: 572: 29.64		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		882071 TCPG_HUMAN (14-540): 0: 574: 33.15		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		610651 TCPA_HUMAN (26-541): 0: 548: 32.08		HDAC1_HUMAN (1-482): 0: 668: 100.00
+	Hs
		610808 TCPA_HUMAN (26-541): 0: 548: 32.08		HDAC2_HUMAN (1-478): 0: 666: 85.92
+	Hs
		188210 TCPE_HUMAN (1-541): 0: 637: 100.00		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sc
		739880 TCPE_YEAST (3-540): 0: 583: 59.89		RPD3_YEAST (8-421): 0: 580: 61.48
+	Hs
		188212 TCPG_HUMAN (14-540): 0: 574: 33.15		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Hs
		188351 TCPH_HUMAN (12-539): 0: 572: 29.64		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		149155 TCPE_SCHPO (4-541): 0: 600: 68.77		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Hs
		188166 TCPA_HUMAN (26-541): 0: 548: 32.08		HDAC3_HUMAN (9-434): 0: 574: 57.94
+	Sp
		148949 TCPG_SCHPO (12-539): 0: 564: 34.21		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sp
		149068 TCPH_SCHPO (7-541): 0: 560: 30.00		PHD1_SCHPO (7-415): 0: 524: 52.91
+	Sc
		823622 TCPE_YEAST (3-540): 0: 583: 59.89		HOS2_YEAST (10-411): 2.73e-171: 491: 50.00
+	Mm
		1009970 TCPE_MOUSE (1-541): 0: 629: 96.30		HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94
+	Mm
		1009921 TCPH_MOUSE (12-539): 0: 577: 29.46		HDAC4_MOUSE (8-406): 1.28e-134: 416: 23.94
+	Hs
		876210 TCPE_HUMAN (1-541): 0: 637: 100.00		HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78
+	Hs
		882203 TCPG_HUMAN (14-540): 0: 574: 33.15		HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78
+	Hs
		1407610 TCPH_HUMAN (12-539): 0: 572: 29.64		HDAC6_HUMAN (16-325): 2.06e-93: 309: 25.78