HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: CD2AP (Q9JLQ0)
CD2-associated protein (Mesenchyme-to-epithelium transition protein with SH3 domains 1) (METS-1)
Gene: CD2AP

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.65 0.60 0.629

The method score is based on:

Property Details
Experiments 15001553, 27474268, 12559036
Identification Methods affinity chromatography technology, two hybrid
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008584 - male gonad development
GO:0017124 - SH3 domain binding
GO:0030424 - axon
and 3 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 913
Mm

1 637
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Rn
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024