HitPredict

Interactor 1: AF10 (P55197)
Protein AF-10 (ALL1-fused gene from chromosome 10 protein)
Gene: MLLT10

Interactor 2: ENL (Q03111)
Protein ENL (YEATS domain-containing protein 1)
Gene: MLLT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.658

Property	Details
Experiments	20203130, 20431927, 15856011
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1068 Hs			1 559
+	Hs
		788017 AF10_HUMAN (1-1068): 0: 845: 100.00		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		317421 AF10_HUMAN (1-1068): 0: 845: 100.00		YETS4_HUMAN (6-138): 1.04e-41: 151: 25.18
+	Hs
		876592 AF17_HUMAN (18-1037): 2.6e-106: 359: 36.29		ENL_HUMAN (1-559): 7.97e-77: 255: 100.00
+	Hs
		788018 AF17_HUMAN (18-1037): 2.6e-106: 359: 36.29		AF9_HUMAN (1-559): 6.95e-74: 247: 52.36
+	Hs
		317422 AF17_HUMAN (18-1037): 2.6e-106: 359: 36.29		YETS4_HUMAN (6-138): 1.04e-41: 151: 25.18
+	Mm
		101452 JADE1_MOUSE (5-617): 6.28e-116: 379: 21.05		F8VPR5_MOUSE (36-507): 8.7e-27: 117: 12.63
+	Hs
		1356824 BRPF3_HUMAN (3-769): 1.56e-99: 342: 17.08		YETS2_HUMAN (3-502): 1.64e-35: 144: 12.96
+	Sc
		715757 NTO1_YEAST (11-253): 9.55e-83: 287: 30.83		TAF14_YEAST (6-176): 3.14e-26: 109: 15.91
+	Hs
		998710 MDC1_HUMAN (256-710): 1.42e-17: 90.8: 13.48		EP300_HUMAN (36-507): 4.29e-30: 128: 10.54
+	Hs
		1056910 MDC1_HUMAN (256-710): 1.42e-17: 90.8: 13.48		CBP_HUMAN (36-507): 4.66e-27: 118: 11.67
+	Dm
		113976 M9PB30_DROME (200-821): 1.02e-16: 88.4: 8.85		M9PB30_DROME (160-482): 3.6e-12: 71.7: 10.35