HitPredict

Interactor 1: ELL (P55199)
RNA polymerase II elongation factor ELL (Eleven-nineteen lysine-rich leukemia protein)
Gene: ELL

Interactor 2: EAF2 (Q96CJ1)
ELL-associated factor 2 (Testosterone-regulated apoptosis inducer and tumor suppressor protein)
Gene: EAF2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	1.00	0.878

Property	Details
Experiments	27058417, 12446457, 32152128, 36036574
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	EAF~ELL
Common GO terms	GO:0005654 - nucleoplasm GO:0006368 - transcription elongation by RNA polymerase II GO:0008023 - transcription elongation factor complex GO:0016607 - nuclear speck
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 260
+	Hs
		876661 ELL_HUMAN (1-621): 0: 833: 100.00		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62
+	Hs
		130168 ELL2_HUMAN (2-620): 0: 772: 45.76		EAF2_HUMAN (1-260): 1.48e-112: 326: 100.00
+	Hs
		130169 ELL2_HUMAN (2-620): 0: 772: 45.76		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62
+	Hs
		1286797 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		EAF2_HUMAN (1-260): 1.48e-112: 326: 100.00
+	Hs
		1295112 ELL3_HUMAN (18-126): 1.49e-30: 125: 31.53		EAF1_HUMAN (1-260): 2.01e-92: 275: 53.62