Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.93 1.00 0.966

The method score is based on:

Property Details
Experiments 26186194, 33961781, 35271311, 28514442, 28199306, 25263562, 35831510
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains WD40~WD40
Common GO terms GO:0005765 - lysosomal membrane
GO:0005829 - cytosol
GO:0031669 - cellular response to nutrient levels
GO:0032008 - positive regulation of TOR signaling
GO:0043231 - intracellular membrane-bounded organelle
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 322
Hs

1 974
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024