HitPredict

Interactor 1: SEC13 (P55735)
Protein SEC13 homolog (GATOR2 complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein)
Gene: SEC13

Interactor 2: A16L1 (Q676U5)
Autophagy-related protein 16-1 (APG16-like 1)
Gene: ATG16L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	30196744, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 322 Hs			1 607
+	Hs
		1074793 TAF5_HUMAN (171-320): 7.18e-23: 101: 14.61		A16L1_HUMAN (1-607): 3.73e-164: 483: 100.00
+	Sp
		999838 TUP11_SCHPO (2-250): 9.63e-58: 198: 20.93		TUP11_SCHPO (6-518): 9.92e-73: 246: 12.61
+	Dm
		1358845 WDS_DROME (90-319): 1.09e-47: 165: 19.57		WDS_DROME (279-565): 1.49e-87: 278: 18.27
+	Hs
		878165 SEC13_HUMAN (1-322): 1.89e-85: 261: 100.00		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Sp
		999842 TUP11_SCHPO (2-250): 9.63e-58: 198: 20.93		TUP12_SCHPO (147-397): 7.24e-31: 129: 13.43
+	Hs
		792935 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		LIS1_HUMAN (99-438): 6.8e-50: 180: 14.98
+	Mm
		925836 LIS1_MOUSE (208-320): 4.41e-24: 103: 20.35		LIS1_MOUSE (99-438): 1.81e-49: 179: 14.98
+	Hs
		1346954 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		NLE1_HUMAN (441-607): 2.75e-43: 163: 20.34
+	Hs
		921751 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		GBB2_HUMAN (165-516): 9.92e-44: 161: 16.62
+	Hs
		903418 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		1239053 FBXW7_HUMAN (87-316): 1.49e-41: 154: 14.72		A16L2_HUMAN (487-605): 8.46e-18: 89: 19.33
+	Mm
		1207757 SEC13_MOUSE (156-317): 3.48e-25: 104: 23.78		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Mm
		1207553 TAF5_MOUSE (171-320): 3.18e-23: 101: 14.61		A16L1_MOUSE (436-605): 2.53e-26: 115: 15.25
+	Hs
		903349 WDR5B_HUMAN (2-194): 1.22e-31: 122: 16.67		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903551 NLE1_HUMAN (196-317): 5.64e-28: 114: 20.49		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		903428 SNR40_HUMAN (3-131): 4.97e-25: 104: 22.22		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		792949 LIS1_HUMAN (208-320): 5.26e-24: 102: 20.35		WDR5_HUMAN (183-393): 4.59e-20: 93.6: 13.45
+	Hs
		1240442 POC1A_HUMAN (5-132): 1.69e-26: 109: 20.31		POC1B_HUMAN (517-604): 3.8e-14: 77: 18.18
+	Hs
		301490 POC1B_HUMAN (2-95): 2.54e-19: 89.8: 29.79		WDR47_HUMAN (315-396): 1.12e-10: 66.7: 22.62