HitPredict

Interactor 1: EIF3B (P55884)
Eukaryotic translation initiation factor 3 subunit B (eIF3b) (Eukaryotic translation initiation factor 3 subunit 9) (Prt1 homolog) (hPrt1) (eIF-3-eta) (eIF3 p110) (eIF3 p116)
Gene: EIF3B

Interactor 2: CSK21 (P68400)
Casein kinase II subunit alpha (CK II alpha) (EC 2.7.11.1)
Gene: CSNK2A1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	35271311, 36736316
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 814 Hs			1 391
+	Hs
		879304 EIF3B_HUMAN (1-814): 0: 830: 100.00		CSK23_HUMAN (1-391): 5.89e-133: 388: 98.47
+	Hs
		586643 EIF3B_HUMAN (1-814): 0: 830: 100.00		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		835614 EIF3B_HUMAN (1-814): 0: 830: 100.00		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12
+	At
		1106339 EIF3B_ARATH (134-808): 1.02e-174: 522: 39.13		MPK4_ARATH (2-371): 4.13e-120: 354: 26.44
+	At
		1106577 EIF3B_ARATH (134-808): 1.02e-174: 522: 39.13		MPK6_ARATH (2-365): 7.83e-119: 352: 23.87
+	At
		1106203 EIF3B_ARATH (134-808): 1.02e-174: 522: 39.13		MPK3_ARATH (22-365): 3.81e-118: 349: 24.44
+	At
		1106453 EIF3B_ARATH (134-808): 1.02e-174: 522: 39.13		MPK5_ARATH (22-364): 4.54e-118: 349: 25.92
+	Sc
		410072 EIF3B_YEAST (139-790): 1.9e-118: 377: 29.36		CSK22_YEAST (2-326): 1.7e-120: 354: 59.51
+	Sc
		410069 EIF3B_YEAST (139-790): 1.9e-118: 377: 29.36		CSK21_YEAST (1-329): 6.88e-113: 336: 54.32
+	At
		1105704 Q9CAT3_ARATH (309-714): 3.63e-114: 358: 20.90		KSG7_ARATH (39-375): 4.65e-118: 349: 27.95
+	At
		1106459 Q9CAT3_ARATH (309-714): 3.63e-114: 358: 20.90		MPK5_ARATH (22-364): 4.54e-118: 349: 25.92
+	Hs
		903116 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		792970 LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73		CSK21_HUMAN (1-391): 2.89e-136: 396: 100.00
+	Hs
		586657 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		CSK22_HUMAN (1-334): 4.14e-119: 351: 85.08
+	Hs
		835628 WDR5_HUMAN (554-729): 7.19e-35: 137: 12.71		GSK3B_HUMAN (39-389): 1.2e-112: 337: 29.12
+	Hs
		625202 LIS1_HUMAN (231-410): 5.42e-23: 104: 10.73		CDK2_HUMAN (36-330): 5.34e-122: 356: 29.74
+	Sc
		584716 TAF5_YEAST (304-498): 7.47e-13: 74.5: 19.61		CSK22_YEAST (2-326): 1.7e-120: 354: 59.51