HitPredict

Interactor 1: ARL4C (P56559)
ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
Gene: ARL4C

Interactor 2: ARL10 (Q8N8L6)
ADP-ribosylation factor-like protein 10
Gene: ARL10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Arf~Arf
Common GO terms	GO:0003924 - GTPase activity GO:0005525 - GTP binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 244
+	Hs
		950473 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		ARF1_HUMAN (70-242): 1.07e-70: 216: 32.57
+	Hs
		574647 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		ARF4_HUMAN (70-242): 5.02e-69: 211: 33.71
+	Hs
		912846 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		ARF6_HUMAN (69-237): 4.36e-69: 211: 33.33
+	Sc
		503044 ARF1_YEAST (2-182): 1.79e-87: 256: 43.09		ARF2_YEAST (70-242): 2.39e-70: 215: 32.00
+	Sc
		580844 ARF2_YEAST (2-183): 4.16e-87: 255: 42.31		ARF2_YEAST (70-242): 2.39e-70: 215: 32.00
+	Dm
		778363 ARF1_DROME (1-181): 2.7e-89: 260: 44.87		ARF4_DROME (69-242): 1.3e-68: 210: 32.39
+	Hs
		950474 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		ARF5_HUMAN (70-242): 4.36e-68: 209: 32.00
+	Sc
		503036 ARF1_YEAST (2-182): 1.79e-87: 256: 43.09		ARF1_YEAST (70-241): 1.43e-69: 213: 33.33
+	Hs
		574648 ARF5_HUMAN (1-182): 2.02e-87: 256: 45.06		ARF4_HUMAN (70-242): 5.02e-69: 211: 33.71
+	Hs
		912847 ARF5_HUMAN (1-182): 2.02e-87: 256: 45.06		ARF6_HUMAN (69-237): 4.36e-69: 211: 33.33
+	Hs
		574643 ARF6_HUMAN (1-181): 9.41e-87: 254: 43.65		ARF4_HUMAN (70-242): 5.02e-69: 211: 33.71
+	Hs
		912837 ARF6_HUMAN (1-181): 9.41e-87: 254: 43.65		RAB1A_HUMAN (78-243): 2.39e-67: 208: 16.96
+	Dm
		185474 ARF1_DROME (1-181): 2.7e-89: 260: 44.87		O18332_DROME (78-243): 9.57e-65: 201: 17.54
+	Hs
		895036 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		RAB2A_HUMAN (78-243): 8.8e-63: 197: 16.37
+	Sc
		350839 ARF1_YEAST (2-182): 1.79e-87: 256: 43.09		YPT1_YEAST (78-244): 3.81e-64: 200: 17.44
+	Hs
		897349 ARF1_HUMAN (1-183): 2.12e-89: 261: 45.46		ARF3_HUMAN (67-242): 1.88e-62: 195: 32.02
+	Hs
		895024 ARF6_HUMAN (1-181): 9.41e-87: 254: 43.65		RAB2A_HUMAN (78-243): 8.8e-63: 197: 16.37
+	Hs
		897350 ARF5_HUMAN (1-182): 2.02e-87: 256: 45.06		ARF3_HUMAN (67-242): 1.88e-62: 195: 32.02