Interactor 1: CDK8 (P49336)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (Mediator complex subunit CDK8) (Mediator of RNA polymerase II transcription subunit CDK8) (Protein kinase K35)
Gene: CDK8
Interactor 2: MED11 (Q9P086)
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11)
Gene: MED11
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.89 | 0.60 | 0.734 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24981860, 35271311, 26496610, 29568061, 23602568, unassigned1655 |
| Identification Methods | affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016592 - mediator complex |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
