Protein: MED11
Mediator of RNA polymerase II transcription subunit 11 (Mediator complex subunit 11) (dMED21)

Gene: MED11
Organism: Drosophila melanogaster
Interactions: 61
UniProt ID: Q9VVS4

Gene Ontology (top 5):
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0016592 - mediator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

58514

MED8
Mediator of RNA polymerase II transcription subunit 8

2

2

High-throughput

0.737

High

1465342

MED22
Mediator of RNA polymerase II transcription subunit 22

2

1

High-throughput

0.737

High

1487440

MED30
Mediator of RNA polymerase II transcription subunit 30

2

2

High-throughput

0.737

High

1487445

MED18
Mediator of RNA polymerase II transcription subunit 18

2

1

High-throughput

0.737

High

1321579

MED6
Mediator of RNA polymerase II transcription subunit 6

3

1

Small-scale

0.650

High

1472615

MED17
Mediator of RNA polymerase II transcription subunit 17

3

1

Small-scale

0.650

High

1019302

MED20
Mediator of RNA polymerase II transcription subunit 20

3

1

Small-scale

0.633

High

1469500

MED28
Mediator of RNA polymerase II transcription subunit 28

1

1

High-throughput

0.575

High

1267072

MED29
Mediator of RNA polymerase II transcription subunit 29

2

1

High-throughput

0.571

High

1269637

MED13
Mediator of RNA polymerase II transcription subunit 13

2

2

High-throughput

0.571

High

1302899

MED31
Mediator of RNA polymerase II transcription subunit 31

2

1

High-throughput

0.571

High

1377804

EBI
F-box-like/WD repeat-containing protein ebi

2

1

High-throughput

0.571

High

1428002

MED10
Mediator of RNA polymerase II transcription subunit 10

2

1

High-throughput

0.571

High

1428111

MED7
Mediator of RNA polymerase II transcription subunit 7

2

1

High-throughput

0.571

High

1482742

MED27
Mediator of RNA polymerase II transcription subunit 27

2

1

High-throughput

0.571

High

1485342

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.571

High

1485609

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

1

High-throughput

0.571

High

1485961

CDK8
Cyclin-dependent kinase 8

2

2

High-throughput

0.571

High

1487441

MED14
Mediator of RNA polymerase II transcription subunit 14

2

1

High-throughput

0.571

High

1487442

MED23
Mediator of RNA polymerase II transcription subunit 23

2

1

High-throughput

0.571

High

1487443

MED16
Mediator of RNA polymerase II transcription subunit 16

2

1

High-throughput

0.571

High

900679

DSH
Segment polarity protein dishevelled

2

0

High-throughput

0.547

High

1261432

Q7JQT8
LD41464p

2

0

High-throughput

0.547

High

1306447

INDRA
Zinc finger protein indra

2

0

High-throughput

0.547

High

1473445

Q9VF03
Brahma associated protein 155 kDa

2

0

High-throughput

0.547

High

1480272

Q9VL29
GEO11246p1

2

0

High-throughput

0.547

High

1487436

BAP60
Brahma-associated protein of 60 kDa

2

0

High-throughput

0.547

High

57003

A1ZAK9
P-element somatic inhibitor, isoform A

1

1

High-throughput

0.479

High

1487446

MED15
Mediator of RNA polymerase II transcription subunit 15

1

1

High-throughput

0.479

High

674059

BRM
ATP-dependent helicase brm

1

0

High-throughput

0.458

High

1484621

Q9VR42
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.458

High

56960

A1ZAK7
LD35640p

1

1

High-throughput

0.445

High

1471841

MED25
Mediator of RNA polymerase II transcription subunit 25

1

1

High-throughput

0.445

High

1483015

MED1
Mediator of RNA polymerase II transcription subunit 1

1

1

High-throughput

0.445

High

1485574

MED24
Mediator of RNA polymerase II transcription subunit 24

1

1

High-throughput

0.445

High

1487348

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.445

High

1487434

MED12
Mediator of RNA polymerase II transcription subunit 12

1

2

High-throughput

0.445

High

197490

O18353
CHIP

1

0

High-throughput

0.426

High

1171923

Q24090
GH08712p

1

0

High-throughput

0.426

High

1303632

OSA
Trithorax group protein osa

1

0

High-throughput

0.426

High

1409401

Q9BIW6
Brahma-associated protein 111kD

1

0

High-throughput

0.426

High

1472589

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

1

0

High-throughput

0.426

High

1487435

Q9VX77
Coiled-coil-helix-coiled-coil-helix domain containing 2, isoform A

1

0

High-throughput

0.426

High

1487444

Q9W3G1
Uncharacterized protein, isoform A

1

0

High-throughput

0.426

High

53601

A1Z813
Secretory 24AB, isoform A

1

1

High-throughput

0.407

High

1482721

Q9VNF8
Protein transport protein SEC23

1

1

High-throughput

0.407

High

1069138

Q0E8D0
IP21319p

2

0

High-throughput

0.310

High

1487437

Q9VYK9
LP16520p

2

0

High-throughput

0.310

High

1321526

ENC
Protein encore

2

0

High-throughput

0.298

High

1346447

MESD
LDLR chaperone boca

2

0

High-throughput

0.298

High

1378945

Q960F7
SD03629p

2

0

High-throughput

0.298

High

1440706

LAR4
La-related protein Larp4B

2

0

High-throughput

0.298

High

1486601

Q9VUB7
PAX-interacting protein 1

2

0

High-throughput

0.298

High

1487439

Q9W0L7
ubiquitinyl hydrolase 1

2

0

High-throughput

0.298

High

1487438

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

84730

UNR
RNA-binding protein Unr

1

0

High-throughput

0.232

Low

1069940

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.232

Low

1265441

Q7K2P3
GH20817p

1

0

High-throughput

0.232

Low

1345939

Q8T4A8
AT07769p

1

0

High-throughput

0.232

Low

1346034

ENA
Protein enabled

1

0

High-throughput

0.232

Low

1486141

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025