HitPredict

Interactor 1: TCPG (P49368)
T-complex protein 1 subunit gamma (TCP-1-gamma) (EC 3.6.1.-) (CCT-gamma) (Chaperonin containing T-complex polypeptide 1 subunit 3) (hTRiC5)
Gene: CCT3

Interactor 2: MKKS (Q9NPJ1)
Molecular chaperone MKKS (Bardet-Biedl syndrome 6 protein) (McKusick-Kaufman/Bardet-Biedl syndromes putative chaperonin)
Gene: MKKS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	20080638
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~Cpn60_TCP1
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0006457 - protein folding GO:0051082 - unfolded protein binding
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 545 Hs			1 570
+	Hs
		882114 TCPG_HUMAN (1-545): 0: 640: 100.00		TCPH_HUMAN (9-531): 2.66e-167: 488: 16.21
+	Hs
		881825 TCPG_HUMAN (1-545): 0: 640: 100.00		TCPG_HUMAN (4-519): 7.64e-164: 479: 19.05
+	Hs
		875863 TCPG_HUMAN (1-545): 0: 640: 100.00		TCPE_HUMAN (1-516): 2.96e-162: 475: 15.54
+	Hs
		881833 TCPG_HUMAN (1-545): 0: 640: 100.00		TCPD_HUMAN (19-515): 4.99e-153: 451: 18.65
+	Mm
		1009917 TCPH_MOUSE (2-540): 0: 587: 31.50		TCPH_MOUSE (9-536): 6.96e-172: 499: 16.19
+	Hs
		1407527 TCPH_HUMAN (2-536): 0: 574: 31.18		TCPH_HUMAN (9-531): 2.66e-167: 488: 16.21
+	Hs
		876140 TCPH_HUMAN (2-536): 0: 574: 31.18		TCPE_HUMAN (1-516): 2.96e-162: 475: 15.54
+	Ph
		237433 THS_PYRHO (2-525): 0: 577: 41.22		THS_PYRHO (6-521): 4.19e-160: 469: 17.86
+	Bt
		98936 TCPH_BOVIN (2-536): 0: 573: 31.37		F1MWD3_BOVIN (1-516): 1.54e-160: 470: 15.54
+	Sc
		810831 TCPG_YEAST (3-530): 0: 575: 58.88		TCPH_YEAST (1-539): 7.76e-155: 456: 15.71
+	Zm
		77613 B4FBP0_MAIZE (2-532): 0: 562: 29.55		B4FBP0_MAIZE (5-529): 1.62e-158: 466: 15.88
+	Hs
		899547 TCPH_HUMAN (2-536): 0: 574: 31.18		TCPD_HUMAN (19-515): 4.99e-153: 451: 18.65
+	Sc
		810822 TCPG_YEAST (3-530): 0: 575: 58.88		TCPE_YEAST (5-495): 9.85e-150: 443: 15.36
+	Dm
		875283 TCPG_DROME (3-545): 0: 572: 69.10		Q9VHL2_DROME (6-523): 2.07e-150: 445: 15.63
+	Dm
		875221 TCPG_DROME (3-545): 0: 572: 69.10		Q7KKI0_DROME (5-516): 2.74e-150: 444: 16.39
+	Sc
		553994 TCPG_YEAST (3-530): 0: 575: 58.88		TCPA_YEAST (15-476): 3.59e-129: 391: 20.33
+	Sc
		810799 TCPG_YEAST (3-530): 0: 575: 58.88		TCPG_YEAST (24-490): 1.78e-120: 367: 16.70
+	Dm
		875291 TCPG_DROME (3-545): 0: 572: 69.10		Q9VK69_DROME (13-479): 2.09e-107: 334: 18.39
+	Sc
		810800 TCPG_YEAST (3-530): 0: 575: 58.88		TCPD_YEAST (13-476): 6.1e-105: 327: 19.26