HitPredict

Interactor 1: RIPK4 (P57078)
Receptor-interacting serine/threonine-protein kinase 4 (EC 2.7.11.1) (Ankyrin repeat domain-containing protein 3) (PKC-delta-interacting protein kinase)
Gene: RIPK4

Interactor 2: FKBP4 (Q02790)
Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (51 kDa FK506-binding protein) (FKBP51) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]
Gene: FKBP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32707033
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	FKBP_C~Pkinase
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 832 Hs			1 459
+	Hs
		972586 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP4_HUMAN (1-459): 1.71e-150: 437: 100.00
+	Hs
		883504 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP5_HUMAN (1-456): 2.91e-138: 406: 54.83
+	Hs
		1034995 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP5_HUMAN (1-456): 2.91e-138: 406: 54.83
+	Hs
		883512 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKBP8_HUMAN (26-337): 2.99e-32: 128: 18.30
+	Hs
		883470 RIPK4_HUMAN (1-832): 0: 726: 100.00		FKB1A_HUMAN (149-249): 2.56e-25: 101: 25.71
+	Hs
		1053188 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKBP8_HUMAN (26-337): 2.99e-32: 128: 18.30
+	Hs
		923838 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		FKB1A_HUMAN (149-249): 2.56e-25: 101: 25.71
+	Hs
		684571 RIPK4_HUMAN (1-832): 0: 726: 100.00		STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51
+	Hs
		685027 Q9H4D1_HUMAN (1-832): 0: 697: 90.75		STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51
+	Hs
		1034933 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		FKBP5_HUMAN (1-456): 2.91e-138: 406: 54.83
+	Hs
		972616 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP4_HUMAN (1-459): 1.71e-150: 437: 100.00
+	Hs
		1035071 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		FKBP5_HUMAN (1-456): 2.91e-138: 406: 54.83
+	Hs
		556701 ANK1_HUMAN (233-737): 6.25e-92: 319: 21.44		FKBP8_HUMAN (26-337): 2.99e-32: 128: 18.30
+	Hs
		684893 ANKK1_HUMAN (342-643): 1.15e-46: 180: 19.47		STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51
+	Hs
		685142 RIPK3_HUMAN (21-371): 4.07e-34: 139: 30.39		STIP1_HUMAN (259-458): 6.41e-12: 69.5: 11.51