HitPredict

Interactor 1: CENPF (P49454)
Centromere protein F (CENP-F) (AH antigen) (Kinetochore protein CENPF) (Mitosin)
Gene: CENPF

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35563538, 37788672
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000922 - spindle pole GO:0001822 - kidney development GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm and 2 others more... GO:0005813 - centrosome GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3114 Hs			1 768
+	Hs
		883898 CENPF_HUMAN (1-3114): 0: 759: 100.00		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		772788 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114121 AKAP9_HUMAN (1201-3083): 1.68e-32: 142: 9.38		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113151 PLEC_HUMAN (1637-3114): 4.94e-21: 104: 8.87		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		157340 CTRO_HUMAN (9-523): 1.94e-13: 79.3: 16.06		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113058 SPTN1_HUMAN (4-1546): 3.69e-13: 78.5: 10.46		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		773179 MYH10_HUMAN (1-419): 1.41e-12: 76.6: 11.19		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113148 EEA1_HUMAN (1949-2674): 4.01e-11: 71.6: 21.32		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		587653 DESP_HUMAN (282-945): 7.12e-11: 70.9: 19.30		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114773 MRCKB_HUMAN (2279-2818): 8.81e-11: 70.5: 21.73		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113878 MY18A_HUMAN (1979-2555): 3.76e-09: 65.1: 18.84		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1035502 CENPE_HUMAN (1-1522): 8.14e-49: 196: 11.54		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		773180 MYH10_HUMAN (1-419): 1.41e-12: 76.6: 11.19		CUL4A_HUMAN (10-768): 0: 801: 38.32
+	Hs
		772787 MYH9_HUMAN (1-876): 2.67e-38: 161: 10.83		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		1115199 EEA1_HUMAN (1949-2674): 4.01e-11: 71.6: 21.32		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Hs
		535936 MYH3_HUMAN (1-782): 1.06e-30: 136: 12.79		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		1112472 SPTN1_HUMAN (4-1546): 3.69e-13: 78.5: 10.46		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		773178 MYH10_HUMAN (1-419): 1.41e-12: 76.6: 11.19		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		587651 DESP_HUMAN (282-945): 7.12e-11: 70.9: 19.30		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		587652 DESP_HUMAN (282-945): 7.12e-11: 70.9: 19.30		CUL2_HUMAN (30-768): 0: 673: 26.17