HitPredict

Interactor 1: FBXW4 (P57775)
F-box/WD repeat-containing protein 4 (Dactylin) (F-box and WD-40 domain-containing protein 4)
Gene: FBXW4

Interactor 2: SKI2 (Q15477)
Superkiller complex protein 2 (Ski2) (EC 3.6.4.13) (Helicase-like protein) (HLP)
Gene: SKIC2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	23658844
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DSHCT~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 412 Hs			1 1246
+	Hs
		786997 SNR40_HUMAN (322-411): 5.98e-14: 74.5: 14.29		MTREX_HUMAN (212-1244): 0: 756: 33.59
+	Hs
		134246 FBW1B_HUMAN (34-411): 3.49e-81: 260: 16.03		DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44
+	Hs
		903541 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		903410 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79
+	Hs
		133956 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44
+	Hs
		1281412 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		1271615 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79
+	Hs
		134154 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44
+	Hs
		272085 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		U520_HUMAN (263-1036): 5.13e-70: 261: 15.29
+	Hs
		272231 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		U520_HUMAN (263-1036): 5.13e-70: 261: 15.29
+	Hs
		1288329 SNR40_HUMAN (322-411): 5.98e-14: 74.5: 14.29		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		1271679 NLE1_HUMAN (328-411): 2.65e-17: 85.6: 11.91		DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79
+	Hs
		1344178 FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83		DDX21_HUMAN (160-967): 3.81e-102: 344: 13.55
+	Hs
		1232187 FBXW7_HUMAN (24-276): 1.51e-43: 163: 14.89		ASCC3_HUMAN (177-1036): 2.58e-64: 243: 15.46
+	Hs
		1271621 SNR40_HUMAN (322-411): 5.98e-14: 74.5: 14.29		DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79
+	Sc
		624089 MET30_YEAST (72-191): 5.44e-11: 66.4: 8.03		DBP2_YEAST (170-627): 3.46e-98: 326: 10.69
+	Hs
		1271700 FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83		DDX17_HUMAN (228-625): 1.84e-95: 324: 10.79
+	Hs
		134256 FBW1A_HUMAN (39-151): 6.54e-10: 62.9: 10.83		DDX3X_HUMAN (114-621): 1.37e-95: 322: 10.44
+	Hs
		272239 SNR40_HUMAN (322-411): 5.98e-14: 74.5: 14.29		U520_HUMAN (263-1036): 5.13e-70: 261: 15.29
+	Hs
		903282 WDR5_HUMAN (1-319): 1.97e-65: 213: 12.61		DDX6L_HUMAN (604-777): 1.01e-18: 94.7: 34.97