Interactor 1: TIRAP (P58753)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2)
Gene: TIRAP

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 14739303
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0034142 - toll-like receptor 4 signaling pathway
GO:0043123 - positive regulation of canonical NF-kappaB signal transduction
GO:0045087 - innate immune response
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 221
Hs

1 427
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024