HitPredict

Interactor 1: TIRAP (P58753)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2)
Gene: TIRAP

Interactor 2: SARM1 (Q6SZW1)
NAD(+) hydrolase SARM1 (NADase SARM1) (hSARM1) (EC 3.2.2.6) (NADP(+) hydrolase SARM1) (EC 3.2.2.-) (Sterile alpha and Armadillo repeat protein) (Sterile alpha and TIR motif-containing protein 1) (Sterile alpha motif domain-containing protein 2) (MyD88-5) (SAM domain-containing protein 2) (Tir-1 homolog) (HsTIR)
Gene: SARM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.90	0.614

Property	Details
Experiments	26592460
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	TIR_2~TIR_2
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009986 - cell surface GO:0035591 - signaling adaptor activity GO:0045087 - innate immune response
Homologous interactions	0