Interactor 1: TIRAP (P58753)
Toll/interleukin-1 receptor domain-containing adapter protein (TIR domain-containing adapter protein) (Adaptor protein Wyatt) (MyD88 adapter-like protein) (MyD88-2)
Gene: TIRAP

Interactor 2: RAGE (Q15109)
Advanced glycosylation end product-specific receptor (Receptor for advanced glycosylation end products)
Gene: AGER

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.47 0.60 0.536

The method score is based on:

Property Details
Experiments 21829704
Identification Methods anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0006954 - inflammatory response
GO:0007166 - cell surface receptor signaling pathway
GO:0009986 - cell surface
GO:0032735 - positive regulation of interleukin-12 production
and 6 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 221
Hs

1 404
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024