HitPredict

Interactor 1: RHG39 (P59281)
Rho GTPase-activating protein 39
Gene: Arhgap39

Interactor 2: CNKR2 (Q80YA9)
Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2)
Gene: Cnksr2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28671696, 34800437
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0098978 - glutamatergic synapse
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1107 Mm			1 1032
+	Hs
		1263849 RHG39_HUMAN (1-1107): 0: 1108: 86.45		CNKR2_HUMAN (1-1032): 0: 1007: 98.45
+	Hs
		1160632 RHG39_HUMAN (1-1107): 0: 1108: 86.45		CNKR3_HUMAN (5-500): 0: 592: 58.60
+	Hs
		1319367 RHG39_HUMAN (1-1107): 0: 1108: 86.45		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		1035143 MYO9B_HUMAN (328-1098): 1.7e-120: 412: 16.57		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		70709 MYO9A_HUMAN (196-1098): 7.46e-109: 377: 15.43		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Hs
		1138019 SYDE2_HUMAN (284-1100): 2.11e-91: 320: 14.05		MPRIP_HUMAN (406-1029): 4.83e-59: 222: 16.85
+	Hs
		1035119 MYO9B_HUMAN (328-1098): 1.7e-120: 412: 16.57		SKAP1_HUMAN (574-667): 8.83e-12: 69.9: 25.51
+	Hs
		70688 MYO9A_HUMAN (196-1098): 7.46e-109: 377: 15.43		SKAP1_HUMAN (574-667): 8.83e-12: 69.9: 25.51
+	Sc
		765865 RGA2_YEAST (434-1102): 1.81e-64: 239: 11.16		BOI2_YEAST (518-763): 2.92e-39: 160: 15.33
+	Hs
		1231299 RHG24_HUMAN (880-1106): 3.85e-60: 222: 29.11		DOC10_HUMAN (527-963): 4.74e-39: 160: 12.45
+	Hs
		1021852 ABR_HUMAN (910-1104): 2.33e-35: 147: 23.01		PKHA4_HUMAN (517-955): 2.35e-44: 175: 13.51
+	Sc
		743193 RGA2_YEAST (434-1102): 1.81e-64: 239: 11.16		BOB1_YEAST (540-677): 8.42e-11: 68.3: 24.69