HitPredict

Interactor 1: ARPC4 (P59998)
Actin-related protein 2/3 complex subunit 4 (Arp2/3 complex 20 kDa subunit) (p20-ARC)
Gene: ARPC4

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 24981860, 33961781, 26496610, 29568061, 35271311
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ARPC4~Actin
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0034314 - Arp2/3 complex-mediated actin nucleation
and 4 others

more...
Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 168
Hs

1 394
+ Dm
+ Hs
+ Dm
+ Hs
+ Sc
+ Sp

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024