HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: RASN (P01111)
GTPase NRas (EC 3.6.5.2) (Transforming protein N-Ras)
Gene: NRAS

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30639242, 30194290
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2390 Hs			1 189
+	Hs
		164548 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		164620 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350082 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		963331 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348621 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349252 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		164591 SPTN2_HUMAN (1-2390): 0: 715: 100.00		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		914014 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		895043 SPTB2_HUMAN (3-2390): 0: 712: 61.09		RAB2A_HUMAN (4-185): 1.53e-73: 222: 31.52
+	Hs
		349783 SPTA1_HUMAN (182-1386): 5.78e-93: 340: 19.37		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		348458 SPTA1_HUMAN (182-1386): 5.78e-93: 340: 19.37		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349049 SPTA1_HUMAN (182-1386): 5.78e-93: 340: 19.37		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		349963 UTRN_HUMAN (19-2308): 3.65e-86: 318: 14.19		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		809121 UTRN_HUMAN (19-2308): 3.65e-86: 318: 14.19		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		350157 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		RASK_HUMAN (16-189): 7.56e-85: 249: 85.71
+	Hs
		1045419 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		RAB35_HUMAN (4-171): 6.96e-84: 247: 34.71
+	Hs
		348654 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		RASN_HUMAN (1-189): 9.9e-80: 236: 100.00
+	Hs
		349308 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64
+	Hs
		914061 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		RB11A_HUMAN (4-184): 1.5e-74: 224: 33.88
+	Hs
		349327 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		RASH_HUMAN (1-188): 8.6e-78: 232: 85.64