HitPredict

Interactor 1: PSB3 (P49720)
Proteasome subunit beta type-3 (Proteasome chain 13) (Proteasome component C10-II) (Proteasome subunit beta-3) (beta-3) (Proteasome theta chain)
Gene: PSMB3

Interactor 2: PSMG2 (Q969U7)
Proteasome assembly chaperone 2 (PAC-2) (Hepatocellular carcinoma-susceptibility protein 3) (Tumor necrosis factor superfamily member 5-induced protein 1)
Gene: PSMG2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 205 Hs			1 264
+	Hs
		700471 PSB8_HUMAN (8-205): 4.54e-67: 208: 22.73		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Hs
		701204 PSB5_HUMAN (8-197): 3.58e-66: 205: 22.63		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Hs
		633762 PSB1_HUMAN (2-205): 2.39e-65: 203: 23.94		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Hs
		681211 PSA2_HUMAN (8-205): 3.14e-64: 199: 14.85		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Hs
		700704 PSA5_HUMAN (8-203): 1.11e-63: 198: 12.20		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Hs
		700534 PSB9_HUMAN (6-200): 1.41e-63: 197: 23.08		PSMG2_HUMAN (1-264): 8.72e-146: 410: 100.00
+	Dm
		822079 PSB1_DROME (2-205): 3.64e-70: 215: 26.51		Q9VEC2_DROME (1-264): 7.71e-111: 321: 25.09
+	Dm
		1472640 PSB3_DROME (1-205): 2.02e-67: 207: 63.90		Q9VEC2_DROME (1-264): 7.71e-111: 321: 25.09
+	Dm
		1264703 Q7K148_DROME (8-195): 2.73e-65: 204: 23.94		Q9VEC2_DROME (1-264): 7.71e-111: 321: 25.09
+	Dm
		47791 A0AQH0_DROME (7-199): 4.7e-66: 204: 24.35		Q9VEC2_DROME (1-264): 7.71e-111: 321: 25.09
+	Dm
		1472639 Q9W470_DROME (6-194): 1.64e-63: 200: 19.05		Q9VEC2_DROME (1-264): 7.71e-111: 321: 25.09