HitPredict

Interactor 1: RUVB1 (P60122)
RuvB-like 1 (EC 3.6.4.12) (49 kDa TATA box-binding protein-interacting protein) (49 kDa TBP-interacting protein) (DNA helicase p50) (Pontin 52) (TIP49a)
Gene: Ruvbl1

Interactor 2: RPAP3 (Q9D706)
RNA polymerase II-associated protein 3
Gene: RPAP3

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	29959317
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	RPAP3_C~TIP49_C
Common GO terms	GO:0005829 - cytosol GO:0097255 - R2TP complex GO:0101031 - protein folding chaperone complex GO:1990062 - RPAP3/R2TP/prefoldin-like complex
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 456 Mm			1 660
+	Hs
		1332520 RUVB1_HUMAN (1-456): 0: 715: 99.78		RPAP3_HUMAN (1-660): 9.56e-117: 365: 77.96
+	Hs
		1332519 RUVB2_HUMAN (2-455): 0: 649: 42.76		RPAP3_HUMAN (1-660): 9.56e-117: 365: 77.96
+	Hs
		175313 RUVB1_HUMAN (1-456): 0: 715: 99.78		OGT1_HUMAN (2-626): 1.4e-64: 232: 13.05
+	Mm
		888062 RUVB1_MOUSE (1-456): 0: 716: 100.00		PPP5_MOUSE (119-253): 3.49e-45: 170: 31.85
+	Hs
		175312 RUVB2_HUMAN (2-455): 0: 649: 42.76		OGT1_HUMAN (2-626): 1.4e-64: 232: 13.05
+	Hs
		685119 RUVB1_HUMAN (1-456): 0: 715: 99.78		STIP1_HUMAN (281-656): 3.05e-23: 106: 15.60
+	Mm
		1141243 RUVB2_MOUSE (2-455): 0: 649: 42.76		PPP5_MOUSE (119-253): 3.49e-45: 170: 31.85
+	Dm
		1358469 RUVB1_DROME (1-455): 0: 668: 79.34		Q9V3E9_DROME (1-284): 1.12e-31: 131: 27.11
+	Dm
		1358465 RUVB2_DROME (5-455): 0: 638: 45.25		Q9V3E9_DROME (1-284): 1.12e-31: 131: 27.11
+	Hs
		685116 RUVB2_HUMAN (2-455): 0: 649: 42.76		STIP1_HUMAN (281-656): 3.05e-23: 106: 15.60