HitPredict

Interactor 1: EIF3E (P60228)
Eukaryotic translation initiation factor 3 subunit E (eIF3e) (Eukaryotic translation initiation factor 3 subunit 6) (Viral integration site protein INT-6 homolog) (eIF-3 p48)
Gene: EIF3E

Interactor 2: EIF3K (Q9UBQ5)
Eukaryotic translation initiation factor 3 subunit K (eIF3k) (Eukaryotic translation initiation factor 3 subunit 12) (Muscle-specific gene M9 protein) (PLAC-24) (eIF-3 p25) (eIF-3 p28)
Gene: EIF3K

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.92	1.00	0.964

The method score is based on:

Property	Details
Experiments	35271311, 28514442, 24981860, 33961781, 17403899, 18599441, 23623729
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	CSN8_PSD8_EIF3K~PCI
Common GO terms	GO:0001732 - formation of cytoplasmic translation initiation complex GO:0003723 - RNA binding GO:0003743 - translation initiation factor activity GO:0005634 - nucleus GO:0005829 - cytosol and 6 others more... GO:0005852 - eukaryotic translation initiation factor 3 complex GO:0006413 - translational initiation GO:0006446 - regulation of translational initiation GO:0016020 - membrane GO:0016282 - eukaryotic 43S preinitiation complex GO:0033290 - eukaryotic 48S preinitiation complex
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1	445
Hs

1	218

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024