HitPredict

Interactor 1: PCBP1 (P60335)
Poly(rC)-binding protein 1 (Alpha-CP1) (Heterogeneous nuclear ribonucleoprotein E1) (hnRNP E1)
Gene: PCBP1

Interactor 2: SRSF3 (P84104)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Protein X16) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	34133714
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005737 - cytoplasm GO:0016607 - nuclear speck
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 356 Mm			1 164
+	Mm
		888818 PCBP1_MOUSE (1-356): 2.47e-107: 320: 100.00		SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55
+	Hs
		951974 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		853900 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		516530 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Mm
		857294 PCBP1_MOUSE (1-356): 2.47e-107: 320: 100.00		TIA1_MOUSE (5-107): 1.59e-18: 82.6: 21.70
+	Hs
		1028924 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44
+	Hs
		951975 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00
+	Hs
		266997 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		853901 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		NCBP2_HUMAN (7-117): 3.6e-25: 96.1: 24.14
+	Hs
		1071898 PCBP1_HUMAN (1-356): 2.47e-107: 320: 100.00		CELF3_HUMAN (5-90): 3.32e-13: 68: 19.15
+	Hs
		516531 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Hs
		993723 PCBP2_HUMAN (1-352): 1.2e-97: 295: 81.44		SRSF4_HUMAN (11-112): 3.43e-16: 76.6: 39.22
+	Mm
		904289 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		SRSF7_MOUSE (7-115): 1.47e-26: 102: 60.55
+	Mm
		904238 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		SRSF3_MOUSE (1-164): 6.39e-27: 100: 100.00
+	Mm
		904278 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		SRSF1_MOUSE (9-80): 1.1e-25: 100: 48.65
+	Mm
		192620 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		SRSF5_MOUSE (10-112): 1.98e-24: 97: 44.34
+	Mm
		904361 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		SRS10_MOUSE (1-164): 2.25e-24: 96.6: 32.54
+	Hs
		516439 HNRPK_HUMAN (7-353): 1.94e-68: 223: 22.51		PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77
+	Mm
		665747 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		PABP1_MOUSE (1-91): 1.3e-20: 89.2: 25.77
+	Mm
		904294 HNRPK_MOUSE (7-353): 1.94e-68: 223: 22.51		RBM4_MOUSE (11-88): 2.36e-18: 82.2: 28.21