Interactor 1: PTEN (P60484)
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (EC 3.1.3.16) (EC 3.1.3.48) (EC 3.1.3.67) (Inositol polyphosphate 3-phosphatase) (EC 3.1.3.-) (Mutated in multiple advanced cancers 1) (Phosphatase and tensin homolog)
Gene: PTEN
Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 0.60 | 0.515 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12176037 |
| Identification Methods | affinity chromatography technology, coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0005886 - plasma membrane GO:0016324 - apical plasma membrane GO:0019899 - enzyme binding GO:0033137 - negative regulation of peptidyl-serine phosphorylation GO:0060070 - canonical Wnt signaling pathway |
| Homologous interactions | 2 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
