Protein: IST3
U2 snRNP component IST3 (Increased sodium tolerance protein 3) (U2 snRNP protein SNU17)

Gene: IST3
Organism: Saccharomyces cerevisiae S288C
Interactions: 35
UniProt ID: P40565

Gene Ontology (top 5):
GO:0000245 - spliceosomal complex assembly
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0000974 - Prp19 complex
GO:0003723 - RNA binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

826521

CWC26
Pre-mRNA-splicing factor CWC26

11

4

Small-scale

0.985

High

826531

CWC2
Pre-mRNA-splicing factor CWC2

3

10

High-throughput

0.805

High

826523

CUS1
Cold sensitive U2 snRNA suppressor 1

2

1

Small-scale

0.789

High

826530

PML1
Pre-mRNA leakage protein 1

7

2

Small-scale

0.748

High

575959

CYPH
Peptidyl-prolyl cis-trans isomerase

1

6

High-throughput

0.691

High

826522

SF3B1
U2 snRNP component HSH155

1

10

Small-scale

0.691

High

826527

RSE1
Pre-mRNA-splicing factor RSE1

1

6

Small-scale

0.691

High

826534

HSH49
Protein HSH49

1

15

Small-scale

0.691

High

826529

RDS3
Pre-mRNA-splicing factor RDS3

3

1

Small-scale

0.656

High

739151

PRP19
Pre-mRNA-processing factor 19

3

13

Small-scale

0.650

High

403544

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

20

High-throughput

0.646

High

744123

BRR2
Pre-mRNA-splicing helicase BRR2

2

16

High-throughput

0.571

High

464329

OAT
Ornithine aminotransferase

1

1

High-throughput

0.536

High

802558

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.536

High

804224

SSZ1
Ribosome-associated complex subunit SSZ1

1

6

High-throughput

0.536

High

815726

SAHH
Adenosylhomocysteinase

1

4

High-throughput

0.536

High

826524

CEF1
Pre-mRNA-splicing factor CEF1

1

4

High-throughput

0.536

High

788419

PGM2
Phosphoglucomutase 2

1

0

High-throughput

0.513

High

453640

PYR1
Multifunctional protein URA2

1

3

High-throughput

0.500

High

597166

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.500

High

561484

TBP
TATA-box-binding protein

1

0

High-throughput

0.486

High

780830

MUD2
Splicing factor MUD2

1

0

Small-scale

0.486

High

628208

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

11

High-throughput

0.479

High

700110

PRP45
Pre-mRNA-processing protein 45

1

4

High-throughput

0.479

High

796445

SLT11
Pre-mRNA-splicing factor SLT11

1

2

High-throughput

0.479

High

826520

PRP17
Pre-mRNA-processing factor 17

1

9

High-throughput

0.479

High

826525

SYF1
Pre-mRNA-splicing factor SYF1

1

12

High-throughput

0.479

High

826532

CLF1
Pre-mRNA-splicing factor CLF1

1

16

High-throughput

0.479

High

826533

PRP46
Pre-mRNA-splicing factor PRP46

1

12

High-throughput

0.479

High

367389

CISY1
Citrate synthase, mitochondrial

1

2

High-throughput

0.457

High

626770

HSP60
Heat shock protein 60, mitochondrial

1

6

High-throughput

0.457

High

510562

HSP77
Import motor subunit, mitochondrial

1

10

High-throughput

0.445

High

818970

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

826528

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

826526

YMU7
Putative uncharacterized protein YMR057C

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025