HitPredict

Interactor 1: GBRL2 (P60521)
Gamma-aminobutyric acid receptor-associated protein-like 2 (GABA(A) receptor-associated protein-like 2) (Golgi-associated ATPase enhancer of 16 kDa) (GATE-16)
Gene: Gabarapl2

Interactor 2: ATG7 (Q9D906)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (APG7-like) (mAGP7) (Ubiquitin-activating enzyme E1-like protein)
Gene: ATG7

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	11890701
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ATG8~ThiF
Common GO terms	GO:0000045 - autophagosome assembly GO:0005829 - cytosol GO:0006995 - cellular response to nitrogen starvation
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 117 Mm			1 698
+	Mm
		1322119 GBRAP_MOUSE (1-117): 7.55e-57: 173: 57.27		ATG7_MOUSE (1-698): 0: 960: 100.00
+	Hs
		311683 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		ATG7_HUMAN (2-698): 0: 943: 93.12
+	Hs
		305873 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		ATG7_HUMAN (2-698): 0: 943: 93.12
+	Hs
		311756 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		ATG7_HUMAN (2-698): 0: 943: 93.12
+	Mm
		1265088 MLP3A_MOUSE (5-117): 2.01e-45: 144: 41.74		ATG7_MOUSE (1-698): 0: 960: 100.00
+	Mm
		1321768 MLP3B_MOUSE (2-116): 2.53e-44: 141: 38.46		ATG7_MOUSE (1-698): 0: 960: 100.00
+	Hs
		311750 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		ATG7_HUMAN (2-698): 0: 943: 93.12
+	Hs
		311758 MLP3A_HUMAN (5-117): 2.01e-45: 144: 41.74		ATG7_HUMAN (2-698): 0: 943: 93.12
+	Hs
		311755 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		ATG7_HUMAN (2-698): 0: 943: 93.12
+	At
		1277811 ATG8D_ARATH (3-117): 3.37e-62: 186: 57.39		ATG7_ARATH (9-686): 0: 775: 45.15
+	At
		1258019 ATG8F_ARATH (2-117): 1.18e-61: 185: 62.07		ATG7_ARATH (9-686): 0: 775: 45.15
+	Dm
		1177993 Q9W2S2_DROME (1-117): 5.35e-58: 176: 57.27		Q7JY94_DROME (9-696): 0: 765: 39.69
+	Ce
		104029 LGG1_CAEEL (1-116): 2.15e-55: 170: 57.76		G5EBK4_CAEEL (11-686): 0: 680: 40.56
+	Sc
		745982 ATG8_YEAST (1-116): 1.06e-58: 178: 56.03		ATG7_YEAST (7-697): 0: 654: 38.02
+	Hs
		891312 GBRL2_HUMAN (1-117): 1.08e-58: 178: 100.00		UBA5_HUMAN (322-590): 8.47e-46: 170: 18.25
+	Hs
		306308 GBRAP_HUMAN (1-117): 7.55e-57: 173: 57.27		UBA5_HUMAN (322-590): 8.47e-46: 170: 18.25
+	Hs
		1326964 GBRL1_HUMAN (1-116): 7.89e-56: 170: 61.21		UBA5_HUMAN (322-590): 8.47e-46: 170: 18.25
+	Hs
		1315800 MLP3C_HUMAN (5-116): 5.09e-45: 144: 42.11		UBA5_HUMAN (322-590): 8.47e-46: 170: 18.25
+	Hs
		1326135 MLP3B_HUMAN (2-117): 6.34e-44: 141: 38.14		UBA5_HUMAN (322-590): 8.47e-46: 170: 18.25
+	Dm
		55857 Q9W2S2_DROME (1-117): 5.35e-58: 176: 57.27		A1ZBA9_DROME (9-70): 6.37e-18: 89.5: 33.87